Quadriceps Tendon vs Peroneus Longus Tendon in ACL Reconstruction
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Anterior Cruciate Ligament Reconstruction Using Quadriceps Tendon Autograft, Anterior Cruciate Ligament Reconstruction Using Peroneus Longus Tendon Autograft.
- Who it may be relevant to
- Registry conditions: Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture. Basic parameters: 18 years — 50 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
A Prospective Randomized Clinical Trial Comparing Quadriceps Tendon and Peroneus Longus Tendon Autografts in Anterior Cruciate Ligament Reconstruction: Clinical, Functional, and Gait Analysis Outcomes
Overview
This prospective randomized clinical trial aims to compare quadriceps tendon and peroneus longus tendon autografts in anterior cruciate ligament reconstruction. Patients with anterior cruciate ligament injury undergoing primary reconstruction surgery will be randomly assigned to one of the two graft groups. Clinical examination findings, return-to-sport outcomes, ankle muscle strength, ankle-related functional scores, and gait analysis parameters will be evaluated at 6 months and 12 months postoperatively. The study aims to investigate both knee-related functional outcomes and donor site morbidity associated with graft harvesting techniques.
Detailed description
Anterior cruciate ligament (ACL) reconstruction is one of the most commonly performed orthopedic procedures for restoring knee stability and enabling return to sports activities after ACL injury. Various autograft options have been described for ACL reconstruction, including hamstring tendon, bone-patellar tendon-bone, quadriceps tendon, and more recently, peroneus longus tendon grafts. Each graft option has unique biomechanical characteristics, advantages, and potential donor site morbidities.
Quadriceps tendon autografts have gained increasing popularity because of their adequate graft diameter, favorable biomechanical properties, and relatively low donor site complications. Peroneus longus tendon autografts have also emerged as a promising alternative graft source with satisfactory clinical outcomes and sufficient graft size. However, concerns remain regarding donor site morbidity, particularly potential effects on ankle muscle strength and ankle function following peroneus longus tendon harvesting.
This prospective randomized study aims to compare quadriceps tendon and peroneus longus tendon autografts in patients undergoing primary ACL reconstruction. Patients will be randomly assigned into two groups according to graft type. Clinical evaluations, functional knee scores, return-to-sport outcomes, ankle muscle strength assessments, ankle-related functional scores, and gait analysis parameters will be assessed during postoperative follow-up.
Follow-up evaluations will be performed at 6 months and 12 months after surgery. The findings of this study are expected to contribute to graft selection strategies in ACL reconstruction by providing comparative data regarding clinical outcomes, functional recovery, gait characteristics, and donor site morbidity.
Interventions
- Procedure Anterior Cruciate Ligament Reconstruction Using Quadriceps Tendon Autograft
Anterior cruciate ligament reconstruction performed using quadriceps tendon autograft. - Procedure Anterior Cruciate Ligament Reconstruction Using Peroneus Longus Tendon Autograft
Anterior cruciate ligament reconstruction performed using peroneus longus tendon autograft.
Primary outcome measures
- International Knee Documentation Committee (IKDC) Subjective Knee Score [Time frame: 12 months postoperatively]
Secondary outcome measures (9)
- Return to Sport Rate [Time frame: Assessment of return to pre-injury level of sports activity following anterior cruciate ligament reconstruction.]
- Ankle Plantar Flexion Strength [Time frame: 6 and 12 months postoperatively]
- Ankle Dorsiflexion Strength [Time frame: 6 and 12 months postoperatively]
- Ankle Inversion Strength [Time frame: 6 and 12 months postoperatively]
- Ankle Eversion Strength [Time frame: 6 and 12 months postoperatively]
- Ankle Rotational Strength [Time frame: 6 and 12 months postoperatively]
- Ground Reaction Force [Time frame: 6 and 12 months postoperatively]
- Force Asymmetry [Time frame: 6 and 12 months postoperatively]
- Weight Distribution [Time frame: 6 and 12 months postoperatively]
Eligibility criteria
Inclusion criteria
- Patients diagnosed with anterior cruciate ligament rupture
- Patients scheduled for primary anterior cruciate ligament reconstruction
- Age between 18 and 50 years
- Ability to provide informed consent
- Willingness to comply with postoperative rehabilitation and follow-up evaluations
Exclusion criteria
- Previous ligament reconstruction surgery on the affected knee
- Multi-ligament knee injuries requiring additional ligament reconstruction
- Severe osteoarthritis of the knee
- Revision anterior cruciate ligament reconstruction
- Neuromuscular disorders affecting lower extremity function
- Active infection
- Inability to comply with follow-up protocol
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Turkey (Türkiye) · 1 center
- Acibadem Fulya Hospital, Sport Medicine Center — Istanbul
Identifiers
NCT: NCT07671729 · Quadriceps vs PL