Laser vs Lontophoresis in KOA
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Low-Level Laser Therapy, Iontophoresis, Conventional Physical Therapy Only.
- Who it may be relevant to
- Registry conditions: Knee Arthritis Osteoarthritis. Basic parameters: 45 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effectiveness of Laser Therapy Versus Lontophoresis in the Management of Knee Osteoarthritis: A Randomized Controlled Trial
Overview
This randomized controlled trial aims to compare the effectiveness of laser therapy and iontophoresis in patients with knee osteoarthritis. The study will evaluate pain reduction, functional improvement, and knee joint mobility following
Detailed description
Participants will be randomly assigned into three groups receiving either laser therapy plus conventional physiotherapy, iontophoresis plus conventional physiotherapy, or conventional physiotherapy alone. Outcome measures will be assessed before and after treatment
Interventions
- Device Low-Level Laser Therapy
Low-level laser therapy combined with conventional physical therapy for patients with knee osteoarthritis to reduce pain and improve functional mobility and knee joint range of motion - Device Iontophoresis
Iontophoresis using dexamethasone combined with conventional physical therapy for patients with knee osteoarthritis to reduce pain and improve physical function and knee joint mobility - Other Conventional Physical Therapy Only
Conventional physical therapy program for patients with knee osteoarthritis including therapeutic exercises, stretching, strengthening exercises, and pain relief modalities to improve knee function and mobility.
Primary outcome measures
- Pain intensity measured using Visual Analogue Scale (VAS) [Time frame: Baseline and after 4 weeks of treatment]
- Functional disability measured using WOMAC. [Time frame: Baseline and after 4 weeks of treatment]
- 3. Knee Range of Motion (ROM). [Time frame: Baseline and after 4 weeks of treatment]
Secondary outcome measures (3)
- Change in physical function assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Physical Function Subscale [Time frame: Baseline (Day 0) and Week 4]
- 2. Reduction of joint stiffness. [Time frame: Baseline and after 4 weeks of treatment]
- Change in daily activities performance assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Physical Function Subscale [Time frame: Baseline (Day 0) and Week 4]
Eligibility criteria
Inclusion criteria
- \* Age 45-65 years.
- Diagnosed primary knee osteoarthritis (Grade I-II).
- Both genders.
- Ability to follow treatment protocol.
Exclusion criteria
- \* Previous knee surgery.
- Intra-articular injections within last 6 months.
- Pacemaker.
- Skin lesions at treatment area.
- Severe neurological or cardiovascular disorders.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07666061 · KFSIRB200-1047