Recruiting NCT07663669
Use of Extracorporeal Photopheresis in Kidney Transplantation: Effects on Antibody-Mediated Rejection
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Antibody-mediated Rejection in Kidney Transplant. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This study aims to describe, over a one-year period, the clinical, biological, and histological evolution of a cohort of kidney transplant recipients who developed antibody-mediated rejection and were treated with extracorporeal photopheresis.
Primary outcome measures
- Number of participants with response to extracorporeal photopheresis (ECP) at 1 year [Time frame: One year after initiation of ECP]
Eligibility criteria
Inclusion criteria
- Kidney transplant recipients followed at the University Hospitals of Besançon and Lille between September 1, 2016, and August 31, 2023
- Patients with antibody-mediated rejection (as confirmed by histological analysis of the renal biopsy)
- Rejection treated with extracorporeal photopheresis
- Subjects who do not object to the use of their personal data and/or biological samples
- Subjects affiliated with, or beneficiaries of, the French social security system
Exclusion criteria
- Patients with acute rejection
- Pregnant women, women in labor, or breastfeeding mothers
- Individuals deprived of liberty by judicial or administrative decision; individuals receiving compulsory psychiatric care; or individuals admitted to a healthcare or social institution for reasons other than research participation
- Minors
- Adults under legal protection or unable to provide informed consent
- Subjects without health insurance coverage
- Subjects currently within an exclusion period from another study, or as listed in the "national volunteer registry"
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
France · 1 center
- Centre Hospitalier Universitaire de Besançon — Besançon
Identifiers
NCT: NCT07663669 · 2026/1082