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Not yet recruiting NCT07661485

Comparing Two Soft Tissues Technique on Piriformis Syndrome Patients

No phase Interventional Piriformis Syndrome Musculoskeletal Abnormalities Sciatica

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Myofascial Release, Post Isometric Relaxation.
Who it may be relevant to
Registry conditions: Piriformis Syndrome, Musculoskeletal Abnormalities, Sciatica. Basic parameters: 20 years — 50 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Pakistan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Effect of Myofascial Release as Compared to Post Isometric Relaxation in Improving Pain and Lower Extremity Function in Piriformis Syndrome

Overview

Piriformis Syndrome is a neuromuscular condition with symptoms of pain, numbness and tingling tracing the route of the sciatic nerve, due to the nerve impingement by the piriformis muscle. Two common manual therapy techniques used to treat musculoskeletal conditions are myofascial release and post-isometric relaxation. The intent of the research is to evaluate the effects of myofascial release (MFR) as compared to post-isometric relaxation (PIR) in improving pain and lower extremity function in piriformis syndrome (LEFS). The study population involved 32 individuals aged between 20 to 50 years who will be randomly assigned to two groups; a group that received MFR and a group that received PIR. Both groups received the baseline treatment for four weeks. The Visual Analog Scale (VAS) will be employed to gauge the amount of pain, while the LEFS was used to measure functional mobility

Detailed description

This is Multiple-center, randomized controlled trail. Participants age 20-50 years with diagnosed piriformis syndrome will be referred from neuro physician and orthopedic department of Madina Teaching hospital (MTH) to Physiotherapy ward, Jafar Physiotherapy Clinic and Madina Specilaists Clinic. After informed consent Participants will be randomly assign to one of two parallel groups using a random number generator. Group A (Experimental): Receive MFR 3 sessions per week for total duration 4 weeks. Group B (Active Comparator) receive the PIR 3 sessions per week for total duration 4 weeks. Outcome measures (pain via VAS, functional status via LEFS) are taken at baseline and end of treatment. Data will be analyzed using Spss version 20.

Interventions

  • Other Myofascial Release
    Myofascial release is performed with the patient positioned in prone lying. The piriformis muscle was identified. Sustained pressure was applied directly to the trigger point/piriformis muscle for 10-100 seconds while the patient actively moved the affected limb repeatedly from internal to external rotation. Kneading strokes parallel to the muscle fibers were then performed for 5 minutes to promote elongation. This sequence was repeated three times.
  • Other Post Isometric Relaxation
    Post-isometric relaxation (PIR) is performed with the patient in supine and the hip in neutral rotation. The affected hip was passively moved into horizontal adduction until a mild stretch was felt, while the lumbar spine was stabilized. The patient performed a gentle isometric contraction into hip abduction for 7-10 seconds, followed by 2-3 seconds of relaxation. The leg was then moved into further adduction to a new barrier.

Primary outcome measures

  • Visual analogue scale [Time frame: Baseline and 4 week post intervention]
Secondary outcome measures (1)
  • Lower Extremity Functional Scale [Time frame: Baseline and 4 week of post intervention]

Eligibility criteria

Inclusion criteria

  • Positive Lasegue sign
  • Positive FAIR test
  • Grade 1-3 tenderness on palpation of piriformis between sacrum and greater trochanter of femur
  • 4 or more pain intensity on the VAS scale

Exclusion criteria

  • Lower extremity injuries including ligament, tendon injuries, muscle strains as well as nerve injuries
  • Systemic diseases including tuberculosis, multiple sclerosis, Parkinson's disease as well as chronic inflammatory conditions
  • Congenital deformities including hip dysplasia, limb length discrepancy, scoliosis and congenital pelvic asymmetry
  • Cognitive issues including dementia, severe depression and severe psychotic disorders
  • Lumbar Radiculopathy
  • SIJ Dysfunction
  • Lower Extremity Fractures
  • Pregnancy
  • Malignancy

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Pakistan · 1 center
  • The University of Faisalabad — Faisalābad

Publications

  • This citation will not be hyperlinked on ClinicalTrials.gov. Aleem A, Arfan MT, Razzaq et al. (2022) Effectiveness of post isometric relaxation versus reciprocal inhibition technique on hamstring muscle flexibility. Annals of King Edward Medical University 28(2): 205-209.
  • Ajimsha MS, Al-Mudahka NR, Al-Madzhar JA. Effectiveness of myofascial release: systematic review of randomized controlled trials. J Bodyw Mov Ther. 2015 Jan;19(1):102-12. doi: 10.1016/j.jbmt.2014.06.001. Epub 2014 Jun 13. PMID 25603749

Identifiers

NCT: NCT07661485 · TUF/EIRB/148/2025

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗