Periodization-Based Strength Exercise Training in İndividuals With Type 2 Diabetes
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Non-linear Periodization-Based Strength Training, Linear Periodization-Based Strength Training, Usual Care.
- Who it may be relevant to
- Registry conditions: Type 2 Diabetes. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
A Comparison of the Effects of Different Periodization-Based Strength Training Programs in Individuals With Type 2 Diabetes Mellitus
Overview
This randomized controlled study aims to compare the effects of different periodization-based strength training approaches in individuals with type 2 diabetes mellitus. Participants will be allocated to non-linear periodization, linear periodization, or control groups. The intervention program will be conducted for 8 weeks and will evaluate exercise capacity, muscle strength, quality of life, body composition, and metabolic parameters.
Detailed description
Type 2 diabetes mellitus is associated with reduced exercise capacity, decreased muscle strength, impaired quality of life, and metabolic dysfunction. Exercise training is recommended as an important component of diabetes management; however, the comparative effectiveness of different strength training periodization approaches remains unclear.
This randomized controlled trial aims to compare the effects of non-linear periodization and linear periodization strength training programs in individuals with type 2 diabetes mellitus. Participants will be randomized into three groups: a non-linear periodization training group, a linear periodization training group, and a control group receiving usual care.
The intervention will be conducted for 8 weeks, three times per week. Outcomes including exercise capacity, muscle strength, body composition, quality of life, and metabolic parameters will be evaluated before and after the intervention period.
Interventions
- Behavioral Non-linear Periodization-Based Strength Training
Participants will perform supervised non-linear periodization-based strength training three times per week for 8 weeks. - Behavioral Linear Periodization-Based Strength Training
Participants will perform supervised linear periodization-based strength training three times per week for 8 weeks. - Other Usual Care
Participants will receive usual care and no structured exercise intervention during the study period.
Primary outcome measures
- Exercise Capacity [Time frame: Baseline and after 8 week]
Secondary outcome measures (8)
- Change in Peripheral Muscle Strength [Time frame: Baseline and after 8 weeks]
- Change in Hand Grip Strength [Time frame: Baseline and after 8 weeks]
- Change in Diabetes Quality of Life Questionnaire Score [Time frame: Baseline and after 8 weeks]
- Change in Body Fat Percentage [Time frame: Baseline and after 8 weeks]
- Change in Skeletal Muscle Mass [Time frame: Baseline and after 8 weeks]
- Change in Resting Metabolic Rate [Time frame: Baseline and after 8 weeks]
- Change in Hemoglobin A1c (HbA1c) [Time frame: Baseline and after 8 weeks]
- Change in Fasting Blood Glucose [Time frame: Baseline and after 8 weeks]
Eligibility criteria
Inclusion criteria
- Adults aged between 18 to 65 years
- Diagnosis of Type 2 Diabetes Mellitus (T2DM)
- Not having participated in any structured exercise program within the last 6 months
- Willingness to participate in the study and provide written informed consent
Exclusion criteria
- Presence of nephropathy, retinopathy, or peripheral neuropathy
- Presence of neurological, cognitive, or orthopedic disorders that may affect outcome measurements
- Severe respiratory disease (Forced Expiratory Volume in the first second \[FEV1\] <35% or Forced Vital Capacity \[FVC\] <50%)
- Presence of ischemic heart disease or peripheral arterial disease
- History of any cardiovascular event within the last 6 months
- Current malignancy
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Turkey (Türkiye) · 1 center
- Baskent University Hospital — Ankara
Identifiers
NCT: NCT07659925 · T2DM-NLP-2026