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Not yet recruiting NCT07655830

Metabolic and Clinical Effects of Hyperchloremia During HoLEP Surgery.

— Observational HoLEP (Holmium Laser Enucleation of Prostate) Hyperchloremia Perioperative Management

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: HoLEP surgery.
Who it may be relevant to
Registry conditions: HoLEP (Holmium Laser Enucleation of Prostate), Hyperchloremia, Perioperative Management. Basic parameters: from 18 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Evaluation of the Metabolic and Clinical Effects of Intraoperative Hyperchloremia in Holmium Laser Enucleation of Prostate (HoLEP) Surgery.

Overview

This study aims to evaluate the changes between preoperative and postoperative serum chloride levels in patients undergoing HoLEP surgery and to investigate the metabolic and clinical effects of this change. The study is observational, and no additional interventions will be performed.

Detailed description

Although isotonic irrigation fluids used in HoLEP surgery reduce the risk of hyponatremia associated with TUR syndrome, high-volume fluid absorption may lead to hyperchloremia and subsequent metabolic acidosis. This prospective, observational, single-center study, conducted at Ankara Bilkent City Hospital, aims to identify early markers of this condition to optimize perioperative management.

Interventions

  • Procedure HoLEP surgery
    All parameters are part of routine clinical practice; no additional examinations are required

Primary outcome measures

  • Change in serum chloride level [Time frame: Perioperative]
Secondary outcome measures (2)
  • irrigation volume [Time frame: Perioperative]
  • Arter blood gas [Time frame: Perioperative]

Eligibility criteria

Inclusion criteria

  • Patients scheduled for elective HoLEP surgery.
  • Patients providing written informed consent

Exclusion criteria

  • Preoperative metabolic acidosis.
  • Advanced renal failure.
  • Emergency surgery.
  • Missing data.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07655830 · TABED1-26-2505

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗