Patient Preferences in Treatment of Haemophilia A With and Without Inhibitors: a Discrete Choice Experiment in Germany
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: No treatment given.
- Who it may be relevant to
- Registry conditions: Haemophilia A. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Germany
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This study aims to generate structured patient preference evidence on prophylactic treatment options for haemophilia A for adults with and without inhibitors to support health technology assessment and benefit evaluation processes. The study will examine how individuals with haemophilia A evaluate trade-offs between treatment effectiveness, safety, and treatment administration characteristics when choosing between prophylactic therapies. Participants will repeatedly choose between hypothetical treatment profiles that differ in clinically relevant attributes and levels.
Interventions
- Other No treatment given
Web-based survey
Primary outcome measures
- Choice of treatment alternative in discrete choice tasks [Time frame: Day 1]
Eligibility criteria
Inclusion criteria
- Informed consent obtained before any study-related activities (study-related activities are any procedure related to recording of data according to the protocol).
- Participant has the mental capacity and sufficient German language proficiency to understand the study procedures and to complete the survey.
- Age above or equal to 18 years at the time of signing informed consent.
- Validated diagnose with haemophilia A, with and without inhibitors.
- Resident in Germany.
Exclusion criteria
- No provision of informed consent in this study.
- Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation
- Age below 18 years at the time of signing informed consent.
- Absence of a diagnosis of haemophilia A.
- No residence in Germany.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Germany · 1 center
- Novo Nordisk Investigational Site — Mainz
Identifiers
NCT: NCT07653139 · DAS-8858 · U1111-1336-6966