Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospective Clinical Study
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: High-Sensitivity Troponin, Cardiac MRI.
- Who it may be relevant to
- Registry conditions: Myocardial Injury, Coronary Artery Disease. Basic parameters: 21 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Prospective Clinical Study for Evaluation of Perioperative Myocardial Injury Using High-Sensitivity Troponin and Cardiac MRI in Patients Undergoing Coronary Artery Bypass Grafting (CABG)
Overview
Perioperative myocardial injury (PMI) following coronary artery bypass grafting (CABG) is associated with postoperative morbidity, mortality, and long-term outcomes. High-sensitivity troponin assays and cardiac MRI offer reliable diagnostic tools for PMI, but evidence regarding optimal diagnostic thresholds and perioperative imaging strategy is limited. This prospective clinical study aims to determine the incidence of perioperative myocardial injury using multimodal assessments including high-sensitivity troponin, electrocardiogram, echocardiography, cardiac MRI, and perioperative cardiovascular events.
Interventions
- Diagnostic test High-Sensitivity Troponin
High-sensitivity troponin levels are measured preoperatively, predischarge, and at 6-month follow-up to assess perioperative myocardial injury. - Diagnostic test Cardiac MRI
A diagnostic assessment panel including high-sensitivity troponin testing, electrocardiography, echocardiography, and cardiac magnetic resonance imaging performed during the perioperative period.
Primary outcome measures
- Incidence of Perioperative Myocardial Injury (PMI) [Time frame: Within 48 hours post-CABG]
Eligibility criteria
Inclusion criteria
- Age ≥ 21 years
- Undergoing CABG for unstable angina
- Able to provide written informed consent
- No major cardiovascular event in the prior 6 months
Exclusion criteria
- Significant hepatic, renal, or other major organ dysfunction
- Pregnancy or breastfeeding
- Withdrawal during the study
- Contraindication to cardiac MRI (metal implants, claustrophobia, etc.)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- the Second Hospital of Jilin University — Changchun
Identifiers
NCT: NCT07650487 · PMICABG