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Recruiting NCT07649031

MRI as Noninvasive Innovative Approach in Detection and Monitoring of Malignant Oral Lesions in Fanconi Anemia Patients

— Observational Fanconi Anemia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: MRIs.
Who it may be relevant to
Registry conditions: Fanconi Anemia. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

This study being done to learn more about the use of medical Magnetic Resonance Imaging (mMRI) and dedicated dental MRI (ddMRI) as a non-invasive diagnosing tool when evaluating potential oral cancerous and precancerous lesions in Fanconi Anemia patients.

Interventions

  • Diagnostic test MRIs
    mMRI and ddMRI

Primary outcome measures

  • sensitivity of mMRI and ddMRI in identifying dysplastic and malignant lesions in FA patients. [Time frame: Immediately after MRI]
  • specificity of mMRI and ddMRI in identifying dysplastic and malignant lesions in FA patients. [Time frame: Immediately after MRI]

Eligibility criteria

Inclusion criteria

  • Patients with a diagnosis of Fanconi Anemia who are willing to participate and willing to have MRIs
  • Willing to provide informed consent

Exclusion criteria

  • Patient without diagnosis of FA
  • Patients with FA who are under the age of 18
  • Unable to tolerate any MRI due to claustrophobia
  • Any contraindication for the MRI
  • Unable to provide informed consent or comply with the study protocol

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 1 center
  • University of Minnesota — Minneapolis

Identifiers

NCT: NCT07649031 · DENT-2025-34242, STUDY00027283

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗