Comparison Immune Response in Paravertebral and Erector Spinal Plane Block in Breast Cancer Patients
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Regional Anesthetic Injection, Blood draw for the laboratory assessment, Blood draw for the laboratory assessment.
- Who it may be relevant to
- Registry conditions: Breast Cancer - Female. Basic parameters: 18 years — 70 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Immunologic Response in Breast Cancer Before and After Application of Paravertebral and Erector Spinae Plane Block
Overview
The goal of this clinical trial is to find the difference in immune response between two types of regional anesthesia in female patients suffering from breast cancer. The main question it aims to answer is there a difference in the immune response between paravertebral block and erector spinal plane block. Hypothresis of the study is that paravertebral block with propofol induces less immune response in surgical treatment of breast cancer patients than erector spinal plane block. Participants will be asked to sign the informant consent. They will be given either paravertebral block or erector spinae plane block with general anesthesia using propofol. Their venous blood will be taken 1 hour prior surgery and 24 and 48 hours after surgery.
Interventions
- Procedure Regional Anesthetic Injection
Draw of venous blood and application of paravertebral and erector spinae plane block - Procedure Blood draw for the laboratory assessment
Draw of venous blood 24 hours after surgery - Procedure Blood draw for the laboratory assessment
Blood draw 48 hours after surgery
Primary outcome measures
- Immune response in two different regional anesthesia techniques [Time frame: From enrollment to 30 days post surgery]
Eligibility criteria
Inclusion criteria
- ASA I and ASA II status, normal BMI
Exclusion criteria
- ASA III and ASA IV status, coagulopathy, chronic opioid use, diabetes, local infection of the skin
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07648810 · uniri-iz-25-239