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Not yet recruiting NCT07646990

Carbohydrate or Protein Drinks Before Exercise in the Heat

No phase Interventional Heat Stress Diet Induced Thermogenesis Protein Consumption

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Protein shake, Carbohydrate shake.
Who it may be relevant to
Registry conditions: Heat Stress, Diet Induced Thermogenesis, Protein Consumption. Basic parameters: 18 years — 45 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

The Impact of Pre-Exercise Meal Composition on Metabolic Heat Production and Thermal Strain During Exercise in a Hot Environment

Overview

This project examines whether consuming a high-protein or high-carbohydrate beverage before exercise in the heat impacts metabolism and heat balance during exercise, with the following research questions: 1. Does a high-protein vs. high-carbohydrate pre-exercise drink impact metabolism and body temperature responses during a treadmill walking in the heat? 2. Does a high-protein or high-carbohydrate drink change oxygen use and heat production during treadmill walking in the heat?

Interventions

  • Dietary supplement Protein shake
    22 oz of a beverage containing 320 kilocalories (60g protein, 6g fat, 8g carbohydrate).
  • Dietary supplement Carbohydrate shake
    22oz of a carbohydrate drink containing 320 kilocalories (75g carbohydrate, 3g protein, \<1g fat)

Primary outcome measures

  • Metabolic Heat Production [Time frame: Measured during 60 minutes of steady state exercise in 36C, 40% humidity]
Secondary outcome measures (4)
  • Core Temperature [Time frame: Measured at rest and following 60 minutes of exercise in a warm (36C, 40% humidity) environment]
  • Urinary NGAL (ng/mL) [Time frame: Following 60 minutes of exercise in a warm environment (36C, 40% relative humidity)]
  • Urine Specific Gravity (USG) [Time frame: Measured before and after 60 minutes of exercise in a warm (36C, 40%RH) environment.]
  • Proteinuria [Time frame: Following 60 minutes of exercise in a warm environment (36C, 40% relative humidity)]

Eligibility criteria

Inclusion criteria

  • Able to walk or run up to 5 mph on a treadmill
  • Able to consume products containing dairy (no allergy or dietary restrictions)

Exclusion criteria

  • Following a diet that excludes any macronutrient group (low-carb or low-fat)
  • Diagnosed cardiovascular or metabolic diseases (hypertension, diabetes)
  • Diagnosed heat illness in past 3 months (heat exhaustion, heat stroke)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Crossover
Masking
Triple blind
Primary purpose
Prevention

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07646990 · FY26-66

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗