The Effects of Tele-Rehabilitation-Based Dual-Task Upper Extremity Training in Patients With Parkinson's Disease

Official title

Investigating the Effects of Tele-Rehabilitation-Based Dual-Task Upper Extremity Training in Patients With Parkinson's Disease

Overview

The aim of this study is to compare the effects of tele-rehabilitation-based synchronous and asynchronous dual-task upper extremity training with clinical based dual-task upper extremity training and conventional single-task upper extremity training in patients with Parkinson's disease. The main questions it aims to answer are: * Whether there are differences in motor symptoms, hand dexterity, upper extremity functions, grip strength, executive functions, daily living activities, and treatment satisfaction between tele-rehabilitation-based synchronous and asynchronous dual-task upper extremity training, clinical-based dual-task upper extremity training, and conventional single-task upper extremity training in patients with Parkinson's disease. * Whether there is a difference in telemedicine satisfaction between tele-rehabilitation-based synchronous and asynchronous dual-task upper extremity training in patients with Parkinson's disease. Researchers will compare conventional single-task upper extremity training, clinical-based dual-task upper extremity training, tele-rehabilitation-based synchronous upper extremity training and tele-rehabilitation-based asynchronous upper extremity training. Participants will: * Receive upper extremity exercise training at the study clinic or home, twice a week for approximately 60 minutes each time, for 6 weeks. * Participate in assessments at the study clinic before and after exercise training.

Interventions

• Other Conventional Single Task Upper Extremity Exercise Training
  Conventional single task upper extremity exercise training at clinical setting. The first 5 minutes of the training session will consist of a warm-up period of stretching and breathing exercises, followed by a cool-down period of the same exercises.Nine different upper extremity activities (using a fork and spoon, tying shoelaces, reaching, throwing a ball, filling water, folding a sheet, drawing shapes, buttoning, and fastening nuts) will be performed for 3 minutes each, in a random order. A 2-
• Other Clinic-Based Dual Task Upper Extremity Exercise Training
  Dual task upper extremity exercise training at clinical setting. The first 5 minutes of the training session will consist of a warm-up period of stretching and breathing exercises, followed by a cool-down period of the same exercises.Nine different upper extremity activities (using a fork and spoon, tying shoelaces, reaching, throwing a ball, filling water, folding a sheet, drawing shapes, buttoning, and fastening nuts) will be performed simultaneously with three randomly selected cognitive task
• Other Tele-Rehabilitation Based Synchronous Dual Task Upper Extremity Exercise Training
  Dual task upper extremity exercise training at patient's home, synchronous with a researcher via tele-rehabilitation method. The first 5 minutes of the training session will consist of a warm-up period of stretching and breathing exercises, followed by a cool-down period of the same exercises.Nine different upper extremity activities (using a fork and spoon, tying shoelaces, reaching, throwing a ball, filling water, folding a sheet, drawing shapes, buttoning, and fastening nuts) will be performe
• Other Tele-Rehabilitation Based Asynchronous Dual Task Upper Extremity Exercise Training
  Dual task upper extremity exercise training at patient's home, asynchronous under a researcher supervision. It will be carried out according to the pre-determined schedule and will be video recorded. The first 5 minutes of the training session will consist of a warm-up period of stretching and breathing exercises, followed by a cool-down period of the same exercises.Nine different upper extremity activities (using a fork and spoon, tying shoelaces, reaching, throwing a ball, filling water, foldi

Primary outcome measures

• Unified Parkinson's Disease Rating Scale (UPDRS) - PART 3 [Time frame: From enrollment to the end of training at 6 weeks]
• Hoehn & Yahr Scale [Time frame: From enrollment to the end of treatment at 6 weeks]
• Nine-Hole Peg Test [Time frame: From enrollment to the end of treatment at 6 weeks]
• Coin Rotation Test [Time frame: From enrollment to the end of treatment at 6 weeks]
• Manual Ability Measure-36 [Time frame: From enrollment to the end of treatment at 6 weeks]
• Grip Strength [Time frame: From enrollment to the end of treatment at 6 weeks]
• Trail Making Test [Time frame: From enrollment to the end of treatment at 6 weeks]
• Unified Parkinson's Disease Rating Scale (UPDRS) - PART 2 [Time frame: From enrollment to the end of treatment at 6 weeks]
• Dual-Task Impact on Daily-Living Activities Questionnaire [Time frame: From enrollment to the end of treatment at 6 weeks]

Secondary outcome measures (2)

• Treatment Satisfaction [Time frame: At end of treatment at 6 weeks]
• Telemedicine Satisfaction Questionnaire [Time frame: At end of treatment at 6 weeks]

Eligibility criteria

Inclusion criteria

• Having been diagnosed with Parkinson's disease by a neurologist according to the UK Brain Bank criteria
• Being in stage 3 or higher according to the Hoehn-Yahr Scale
• Having a caregiver capable of providing the necessary assistance during tele-rehabilitation sessions and using the required equipment and programs.
• Having the device and software to conduct remote video calls for tele-rehabilitation

Exclusion criteria

• Presence of a neurological disease other than Parkinson's disease
• Cognitive impairment (Standardized Mini Mental Test score less than 24)
• Having undergone deep brain stimulation surgery
• Having a visual, auditory, or perceptual problem
• Having any orthopedic, rheumatological, or other condition that may affect hand functions

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation

Randomized

Model

Parallel assignment

Masking

Single blind

Primary purpose

Supportive care

Study locations

Turkey (Türkiye) · 1 center

• Gülhane Faculty of Physiotherapy and Rehabilitation — Ankara

Identifiers

NCT: NCT07641556 · 2026-151

Primary sources (government registries)

• ClinicalTrials.gov (US NIH)

View this study on ClinicalTrials.gov ↗