Not yet recruiting NCT07639060
Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Chronic Pain, PERIPHERAL NEUROPATHY, Occipital Neuralgia, Chronic Hip Pain. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
To prospectively describe patient-centered and health utilization outcomes through 12 months after cryoneurolysis performed as routine clinical care for chronic pain at Yale.
Primary outcome measures
- Percentage of participants with improvement in pain [Time frame: 6 and 12 months]
- Change in Pain Disability Index (PDI) score [Time frame: 6 and 12 months]
Secondary outcome measures (4)
- Number of pain-related hospital admissions [Time frame: up to 12 months post cryoneurolysis]
- Number of pain-related emergency department visits [Time frame: up to 12 months post cryoneurolysis]
- Number of pain-related medication refills [Time frame: up to 12 months post cryoneurolysis]
- Number of responders [Time frame: 6 and 12 month]
Eligibility criteria
Inclusion criteria
- Diagnosis of chronic pain (generally pain duration of at least 3-6 months) localized to an anatomical region appropriate for cryoneurolysis as determined by the treating physician.
- Planned cryoneurolysis procedure as part of standard clinical care.
- Ability to provide written informed consent.
- Ability and willingness to complete baseline and follow-up questionnaires.
Exclusion criteria
- Cryoneurolysis performed as part of a separate investigational trial in which data sharing is not permitted.
- Active infection or other clinical contraindication to the procedure as determined by the treating clinician.
- Life expectancy of less than 12 months in the judgment of the treating clinician.
- Any condition that, in the investigator's opinion, would interfere with study participation or completion of follow-up, such as severe psychiatric instability or active substance use that precludes reliable follow-up
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07639060 · 2000042295