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Enrolling by invitation NCT07638735

eAMS-Eco: Implementation of a Tool for Climate Conscious Inhaler Prescribing

No phase Interventional Asthma Management Asthma Computerized Decision Support System Primary Care

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Climate-Conscious Clinical Decision Support System for Asthma Management.
Who it may be relevant to
Registry conditions: Asthma Management, Asthma, Computerized Decision Support System, Primary Care. Basic parameters: from 16 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Canada
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

eAMS-Eco: Implementation of a Climate Conscious Prescribing Aid at the Point-of-Care

Overview

The goal of this study is to determine whether an 'eco' version of the Electronic Asthma Management System (eAMS) can reduce inhaler carbon emissions in primary care, in patients with asthma. The existing eAMS uses patient-specific criteria (asthma control, asthma flare-up risk, and current medications) to provide guideline-based computerized clinical decision support to clinicians, to improve the delivery of asthma care. The eAMS-Eco includes embedded cues and messaging on the environmental impact of inhaler medications and links to a patient-friendly conversation aid that facilitates shared decision-making and climate-conscious prescribing. The study will evaluate the implementation of the eAMS-Eco in two primary care clinics that have been using the existing eAMS, using an interrupted time-series analysis (one year pre- and post-launch of the eAMS-Eco). The investigators will assess system uptake and user feedback on the eAMS-Eco, as well as changes in inhaler prescriptions (including resulting changes in carbon emissions and costs) and changes in asthma control, in the implementation period (eAMS-Eco) compared to the baseline period (eAMS).

Detailed description

Climate change poses a significant threat to human health and yet healthcare itself contributes substantially to climate change. Reducing the carbon emissions from healthcare is one actionable step to combat the climate crisis. In regards to asthma care, reductions in carbon emissions could be achieved by addressing the unnecessary of metered-dose inhalers (MDIs), the propellants in which contain potent greenhouse gases. This could be achieved by preferentially prescribing inhaler devices such as dry powder inhalers (DPIs) and soft mist inhalers (SMIs), which do not use propellants and have much lower carbon footprints than MDIs. These devices are almost always available in the same medication classes as MDIs (sometimes with the same active ingredient) and demonstrate comparable clinical efficacy and patient acceptability. Yet MDIs still account for the majority of prescribed inhalers.

The investigators will leverage the existing Electronic Asthma Management System (eAMS), a computerized decision support system (CDSS) that recommends guideline-based medication changes based on assessment of the patients' asthma control and exacerbation risk, to promote climate-conscious prescribing at the point-of-care. When tested in real-world settings, the eAMS improved the quality of asthma care, with a significant increase in the provision of asthma action plans, assessment of asthma control, use of guideline-based inhaler medications, including escalation of controller therapy when indicated. Subsequently, the tool has been used widely in primary care sites in Ontario. To address the issue of inhaler GHG emissions, our team has now created an enhanced version of the existing eAMS, called the 'eAMS-Eco'.

The eAMS-Eco has embedded cues and messaging that indicate the relative carbon footprint of each medication recommended by the eAMS, to provide clinicians with the knowledge needed to enact climate-conscious prescribing. A an orange or red leaf appears next to the recommended medication with hover text indicating that the device has a moderate or high carbon footprint, respectively. The medication name and hover text are clickable links which take the clinician to an inhaler conversation aid, which serves to promote shared decision-making by presenting the carbon footprint (as the equivalent to kilometers driven in a gas powered car) and cost of each inhaler in the corresponding medication class, along with usage details (dosing, number of inhalations per dose, number of doses per device). The conversation aids also include information on inhaler contents (active ingredients) and include a safety warning that emphasizes the importance of considering patient-level factors, such as adequate technique, age, disease severity, and the impact on adherence, when selecting an inhaler device.

Ultimately, the eco-features added to the eAMS are designed to promote climate-conscious prescribing of inhalers while considering the preference and ability of each individual patient. Our study will evaluate the implementation of the eAMS-Eco in two primary care clinics which are already using the eAMS, with an overall goal of reducing inhaler emissions in the primary care of patients with asthma.

Interventions

  • Behavioral Climate-Conscious Clinical Decision Support System for Asthma Management
    An 'eco' version of a computerized clinical decision support system that provides information on the carbon footprint of inhalers when making guideline-based treatment recommendations for patients with asthma

Primary outcome measures

  • Prescribed inhaler carbon emissions [Time frame: 24 months, cumulative and broken into individual time periods]
  • Proportion of low carbon footprint inhalers to moderate/high carbon footprint inhalers prescribed [Time frame: 24 months, cumulative and broken into individual time periods]
Secondary outcome measures (10)
  • Cost of prescribed inhalers [Time frame: 24 months, cumulative and broken into individual time periods]
  • System usage: conversation aid access [Time frame: 12 months, cumulative and broken into individual time periods]
  • System usage: decision-support access [Time frame: 24 months, cumulative and broken into individual time periods]
  • Quantitative patient Likert-Scale questionnaire [Time frame: 12 months]
  • Patient feedback: 4-item Shared Decision-Making Process Scale [Time frame: 12 months]
  • Qualitative patient free-text feedback questionnaire [Time frame: 12 months]
  • Quantitative provider Likert-Scale questionnaire [Time frame: 12 months]
  • Provider feedback: 10-item System Usability Scale [Time frame: 12 months]
  • Qualitative provider free-text feedback questionnaire [Time frame: 12 months]
  • Asthma Control [Time frame: 24 months, cumulative and broken into individual time periods]

Eligibility criteria

Clinician eligibility criteria:

Inclusion criteria

-Active clinician at one of the two study sites during the study period

Patient eligibility criteria:

Inclusion criteria

  • Patient at one of the two study sites with a visit during the study period
  • Diagnosis of asthma (using validated algorithm for primary care of
  • asthma billing code (493) in the past 3 years OR asthma in the cumulative patient profile (CPP) and
  • prescription for an inhaler in the past year

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Non-randomized
Model
Sequential
Masking
Open label
Primary purpose
Health services research

Study locations

Canada · 2 centers
  • Taddle Creek Family Health Team (Bay Street) — Toronto
  • Taddle Creek Family Health Team (Bloor Street) — Toronto

Identifiers

NCT: NCT07638735 · 25-271

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗