Recruiting NCT07637331
The Effect of Respiratory Muscle Training on Cognitive Performance
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Inspiratory muscle training.
- Who it may be relevant to
- Registry conditions: Respiratory Muscle Training. Basic parameters: 18 years — 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Determine if exercise training for the respiratory muscles improves cognitive performance during periods when breathing against a resistance.
Interventions
- Device Inspiratory muscle training
8 weeks of active or sham inspiratory muscle training
Primary outcome measures
- Diaphragm thickness [Time frame: Baseline and after 8 weeks of training]
- Cognitive performance [Time frame: Baseline and after 8 weeks of training]
Secondary outcome measures (1)
- Dyspnea [Time frame: Baseline and after 8 weeks of training]
Eligibility criteria
Inclusion criteria
- 18-40 years old
- Body mass index <30 kg/m2
- Naïve to IMT
- >75% of predicted forced expiratory volume in 1 second (FEV1) / forced vital capacity (FVC) (FEV1/FVC)
- Access to smart phone or tablet with internet
Exclusion criteria
- Diagnosed:
- Cardiovascular disease
- Respiratory disease (including asthma)
- Metabolic disease
- Currently pregnant
- Unable to adhere to the IMT protocol
- Answering 'yes' to any of the questions on page one of the PAR-Q+
- Abnormal cognition assessed via the Montreal Cognitive Assessment (score of 25 or less)
- Self-reported color blindness
- Significant acute or chronic medical, neurologic, or illness in the participant that, in the judgment of the Principal Investigator, could compromise subject safety, limit the ability of the participant to complete the study, and/or compromise the objectives of the study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Prevention
Study locations
United States · 1 center
- Indiana University — Bloomington
Identifiers
NCT: NCT07637331 · 28083