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Recruiting NCT07634640

Hearts on Fire: Targeting Inflammation in Heart Failure With Preserved Ejection Fraction

Early Phase I Interventional Heart Failure With Preserved Ejection Fraction (HFPEF)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Ferumoxytol infusion.
Who it may be relevant to
Registry conditions: Heart Failure With Preserved Ejection Fraction (HFPEF). Basic parameters: 18 years — 85 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Omega-3 Fatty Acids and Myocardial Inflammation in HFpEF: Preliminary Data and Next Steps

Overview

Subjects undergo a gadolinium-based CMR followed by an iron infusion and then a repeat CMR in 72 hours

Interventions

  • Drug Ferumoxytol infusion
    Ferumoxytol infusion followed by cardiac MRI

Primary outcome measures

  • detection of inflammation [Time frame: 72 hours]

Eligibility criteria

Inclusion criteria

  • HFpEF

Exclusion criteria

  • Renal insufficiency

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Other

Study locations

United States · 1 center
  • University of Florida — Gainesville

Identifiers

NCT: NCT07634640 · 202300847 · 26BIPA1622606

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗