Study on the Effect of Hyperbaric Oxygen Intervention on Relieving Sports Fatigue of Sailors
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Mild Hyperbaric Oxygen Therapy.
- Who it may be relevant to
- Registry conditions: Elite Male Sailing Athletes. Basic parameters: 18 years — 35 years · Male.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
1. Research Purpose Intensive training often causes autonomic nerve imbalance, poor microcirculation and slow fatigue recovery in elite sailing athletes. This study adopted 1.3 ATA mild hyperbaric oxygen with 28% oxygen concentration for a 6-week intervention. It aimed to explore whether mild hyperbaric oxygen can improve athletes' autonomic nerve function, microcirculation and fatigue-related biochemical indicators. Meanwhile, it intended to estimate the effect size, provide basis for future large-scale formal trials, and optimize fatigue recovery strategies for sailing athletes and other endurance athletes. 2. Study Population A total of 16 elite male sailing athletes were enrolled and randomly divided into two groups with 8 participants in each group. Inclusion criteria: aged over 18 years; holding national first-class athlete certificate or above; participating in systematic sailing training at least 5 times a week with more than 5 years of professional training experience. Those with cardiovascular diseases, absolute contraindications to hyperbaric oxygen, training suspension due to injury and other ineligible conditions were excluded. 3. Primary Outcome Measures Autonomic nerve function: Heart rate variability (HRV) indicators were tested to observe whether hyperbaric oxygen balances sympathetic and parasympathetic nerves and relieves training-induced autonomic disorder. Microcirculation function: Measured muscle microcirculation blood flow velocity, capillary perfusion and thermal stimulation microvascular reserve capacity to evaluate the improvement of peripheral blood circulation. Fatigue and biochemical biomarkers: Routine blood indexes: red blood cell, hemoglobin, white blood cell; Exercise injury and metabolic indexes: creatine kinase (CK), blood urea nitrogen (BUN), testosterone and cortisol; Oxidative stress indexes: malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), to assess the body's oxidation-antioxidant status, inflammation level and fatigue recovery degree.
Interventions
- Device Mild Hyperbaric Oxygen Therapy
Participants receive mild hyperbaric oxygen therapy (mHBOT) in a hyperbaric chamber at 1.3 atmospheres absolute (ATA) with 28% oxygen concentration, for 60 minutes per session, 5 sessions per week over 6 weeks. All participants continue their standard sailing training regimen throughout the study.
Primary outcome measures
- Change in Heart Rate Variability (HRV) [Time frame: Baseline (Week 0), Post-intervention (Week 6)]
Eligibility criteria
Inclusion criteria
- Male elite sailing athletes aged 18-35 years
- Holding a national first-class athlete certificate or above
- With at least 5 years of professional sailing training experience
- Engaging in regular sailing training ≥ 5 times per week
- Voluntarily sign the informed consent form
Exclusion criteria
- \- Presence of cardiovascular, respiratory, or neurological diseases
- Absolute contraindications to hyperbaric oxygen therapy
- Current injury or illness requiring medical treatment or training suspension
- Use of any medications or supplements that may affect fatigue recovery or autonomic function
- Participation in other concurrent recovery interventions during the study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07625696 · LLSC20250004