TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: trans rectus sheath extra-peritoneal procedure (TREPP).
- Who it may be relevant to
- Registry conditions: Inguinal Hernia, Inguinal Hernia Repair. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair: A Single-center Prospective Study.
Overview
Inguinal hernia repair remains one of the most commonly performed surgical procedures worldwide. Tension-free repair with mesh augmentation is the predominant treatment option, either achieved by preperitoneal laparoscopic hernioplasty or Lichtenstein procedure (LP). As the recurrence rate is reduced to less than 5 % after mesh repair, nowadays, long-term morbidity associated with open inguinal hernia repair is mainly related to chronic postoperative inguinal pain (CPIP). Despite many hypotheses about the possible causes for CPIP, there is now consensus that involvement of inguinal nerves plays a major role. The trans rectus sheath extra-peritoneal procedure (TREPP) is a minimally invasive open approach utilizing the rectus sheath to access the preperitoneal space. It has shown promise in providing effective repair with potential advantages in cosmesis, postoperative pain, and recurrence rates. It is a medial approach avoiding the interference with the course of all (three) inguinal nerves through lateral abdominal wall.
Detailed description
This is a prospective cohort study
Interventions
- Procedure trans rectus sheath extra-peritoneal procedure (TREPP)
The TREPP technique, a minimally invasive open approach utilizing the rectus sheath to access the preperitoneal space
Primary outcome measures
- Recurrence rate [Time frame: through study completion, an average of 1 year]
Secondary outcome measures (1)
- Incidence of chronic postoperative inguinal pain [Time frame: 3 months after surgery]
Eligibility criteria
Inclusion criteria
- Adults with primary unilateral or bilateral inguinal hernia
Exclusion criteria
- Strangulated hernias.
- Severe comorbidities precluding surgery ((ASA Class IV,V)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Faculty of Medicine-Assiut University -Assiut-Egypt — Asyut
Publications
- Faessen JL, Stoot JHMB, Broos PPHL, Vijgen GHEJ, Reisinger KW, Bouvy ND, van Vugt R. Trans rectus sheath extra-peritoneal procedure (TREPP) for inguinal hernia repair under local anesthesia with sedation in the outpatient clinic: a feasibility study. Langenbecks Arch Surg. 2024 Jun 19;409(1):188. doi: 10.1007/s00423-024-03383-z. PMID 38896330
- Bokkerink WJ, Persoon AM, Akkersdijk WL, van Laarhoven CJ, Koning GG. The TREPP as alternative technique for recurrent inguinal hernia after Lichtenstein's repair: A consecutive case series. Int J Surg. 2017 Apr;40:73-77. doi: 10.1016/j.ijsu.2017.02.022. Epub 2017 Feb 20. PMID 28219816
- Faessen JL, Stoot JHMB, van Vugt R. Safety and efficacy in inguinal hernia repair: a retrospective study comparing TREPP, TEP and Lichtenstein (SETTLE). Hernia. 2021 Oct;25(5):1309-1315. doi: 10.1007/s10029-020-02361-w. Epub 2021 Jan 5. PMID 33400030
- Bokkerink WJV, Koning GG, Vriens PWHE, Mollen RMHG, Harker MJR, Noordhof RK, Akkersdijk WL, van Laarhoven CJHM. Open Preperitoneal Inguinal Hernia Repair, TREPP Versus TIPP in a Randomized Clinical Trial. Ann Surg. 2021 Nov 1;274(5):698-704. doi: 10.1097/SLA.0000000000005130. PMID 34342299
- Eklund AS, Montgomery AK, Rasmussen IC, Sandbue RP, Bergkvist LA, Rudberg CR. Low recurrence rate after laparoscopic (TEP) and open (Lichtenstein) inguinal hernia repair: a randomized, multicenter trial with 5-year follow-up. Ann Surg. 2009 Jan;249(1):33-8. doi: 10.1097/SLA.0b013e31819255d0. PMID 19106673
Identifiers
NCT: NCT07618884 · RF-1-6-2025