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Not yet recruiting NCT07617714

Adapted Physical Activity (APA) Following Hospitalization in Frail Older Adults

No phase Interventional Oncologic Disease

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Adapted Physical Activity Program, routine care.
Who it may be relevant to
Registry conditions: Oncologic Disease. Basic parameters: from 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

To evaluate the effectiveness of an Adapted Physical Activity (APA) program in improving functional capacity and reducing frailty in older adults following hospital discharge. The aim is to determine whether a structured program of personalized exercises improves mobility, strength, and quality of life compared to standard care.

Interventions

  • Other Adapted Physical Activity Program
    a 14-week Adapted Physical Activity (APA) program following hospital discharge
  • Other routine care
    Participants in the control group will receive standard post-discharge care, along with general recommendations for physical activity and healthy lifestyle habits

Primary outcome measures

  • Improvement in overall physical function assessed by changes in the Short Physical Performance Battery (SPPB) score." [Time frame: 4 months]

Eligibility criteria

Inclusion criteria

  • The study is open to individuals aged 65 and older.
  • Current diagnosis or recent history of cancer.
  • Patients currently undergoing treatment (chemotherapy, immunotherapy, targeted therapy) or in follow-up after recent treatment (≤12 months since completion).
  • Functional capacity compatible with participation in an adapted physical activity program, as determined by clinical assessment.
  • Recent hospitalization: Patients must have been discharged following a hospital stay.
  • Frailty: Presence of a significant level of frailty at hospital discharge.

Exclusion criteria

  • Short Physical Performance Battery> 10: Patients considered "robust" are excluded to maximize the relevance of the intervention.
  • Acute unstable medical condition or contraindication to exercise: Any unstabilized acute condition that makes physical activity dangerous (e.g., acute cardiac complication, ongoing severe infection). Recent major medical events (myocardial infarction, major surgery, bone fracture, or major amputation in the past few weeks) will also be excluded.
  • Severe chronic conditions incompatible with exercise: Severe progressive diseases that prevent safe exercise, such as severe neuromuscular diseases or advanced organ failure (e.g., end-stage renal failure).
  • Short-term life-threatening prognosis: Patients in the terminal phase or with a very limited life expectancy (less than 6 months).
  • Total functional dependence or severe motor impairment: Patients who are completely dependent for basic activities (very low Barthel Index, e.g., <20/100) or who are unable to move even minimally (e.g., unable to walk a few steps or stand, even with assistance).
  • Severe cognitive impairment: Severe cognitive impairment (e.g., advanced dementia without the ability to follow simple instructions) that prevents active participation in the program.
  • Severe sensory or communication disorders: Significant sensory impairments-such as profound uncompensated blindness or deafness-or any communication barrier (severe aphasia, language barrier) that prevents participation in the program, unless a caregiver (family member or professional) can be present to ensure safety during the exercises.
  • Institutionalization of the patient: Individuals who do not live in their usual residence are excluded. The study focuses on older adults returning home, as the institutional setting involves different care.
  • Lack of valid informed consent: Any patient who refuses to participate or who cannot provide valid consent (due to lack of legal capacity or understanding) will be excluded.
  • Participation in another concurrent program or trial: Simultaneous participation in another physical exercise program or trial.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Other

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07617714 · SHAPE

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗