HFNC Versus Microstream Advance Nasal Cannula for Oxygenation During ERCP
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: High-flow nasal canula, Microstream advance nasal cannula.
- Who it may be relevant to
- Registry conditions: Endoscopic Retrograde Cholangiopancreatography, Hypoxemia. Basic parameters: 18 years — 84 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Endoscopic retrograde cholangiopancreatography (ERCP) procedures are commonly performed under deep sedation and are associated with a risk of hypoxemia, particularly in prone or semi-prone positions. High-flow nasal cannula (HFNC) therapy may improve oxygenation by delivering heated and humidified oxygen at high flow rates, while the Microstream Advance nasal cannula provides simultaneous nasal oxygen delivery and oral oxygen insufflation. This prospective randomized study aims to compare the effectiveness of HFNC and Microstream Advance nasal cannula in maintaining oxygenation during ERCP procedures. Patients undergoing ERCP will be randomized into two groups receiving either HFNC or Microstream Advance nasal cannula oxygen support during sedation. The primary outcomes are the incidence of desaturation and oxygen reserve index (ORi) measurements during the procedure. Secondary outcomes include time to achieve target ORi levels, respiratory complications, and procedure-related adverse events.
Interventions
- Device High-flow nasal canula
Heated and humidified high-flow oxygen therapy delivered through a nasal cannula during ERCP under sedation - Device Microstream advance nasal cannula
Oxygen support delivered through the Microstream Advance nasal cannula during ERCP under sedation.
Primary outcome measures
- Incidence of Desaturation During ERCP [Time frame: During the ERCP procedure]
Eligibility criteria
Inclusion criteria
- Patients aged 18 to 84 years
- ASA physical status I-III
- Patients scheduled to undergo ERCP
- Patients who provide written informed consent
Exclusion criteria
- Recent history of upper respiratory tract infection
- History of lung cancer
- Chronic obstructive pulmonary disease
- Asthma
- Body mass index greater than 35 kg/m²
- Refusal to participate in the study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Supportive care
Study locations
Turkey (Türkiye) · 1 center
- Kocaeli University Faculty of Medicine Hospital — Kocaeli
Identifiers
NCT: NCT07611903 · KAEK 2024116.b1.03