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Recruiting NCT07611526

Investigation of the Individual Fatigue Response During Blood Flow Restriction Training

No phase Interventional Total Knee Anthroplasty

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Cycling BFR.
Who it may be relevant to
Registry conditions: Total Knee Anthroplasty. Basic parameters: 18 years — 85 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Germany
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Investigation of the Individual Fatigue Response During Blood Flow Restriction Training on a Cycle Ergometer Following Orthopedic Surgical Interventions

Overview

The aim of the present pilot study is to investigate the feasibility of an exercise pressure response approach for assessing physiological strain during BFR training in a clinically supervised setting. Patients undergoing rehabilitation following total knee arthroplasty (TKA) will be included. The results are intended to contribute to an improved evaluation of load management during BFR training.

Interventions

  • Device Cycling BFR
    Cycling ergometer with blood flow restriction

Primary outcome measures

  • Exercise Pressure Response [Time frame: Baseline, continuous analysis throughout the entire training session until immediately after it ends (post-workout)]
Secondary outcome measures (1)
  • Muscle Strength [1RM] [Time frame: Baseline- vs. immediately after the exercise (Pre-Post-Comparison)]

Eligibility criteria

Inclusion criteria

  • Elective TKA caused by osteoarthritis of the knee
  • Ability to perform cycling exercise
  • Participant of the Rehab center

Exclusion criteria

  • Open Wounds
  • Iatrogenic Vessel Changes (e.g. Bypasses, Stenting)
  • Sickle Cell Anemia

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Crossover
Masking
Triple blind
Primary purpose
Diagnostic

Study locations

Germany · 1 center
  • University Hospital Bonn — Bonn

Identifiers

NCT: NCT07611526 · 2026_A

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗