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Recruiting NCT07608120

Electrolyte Beverage Combined With Polyethylene Glycol for Colonoscopy Bowel Preparation

No phase Interventional Colonoscopy Bowel Preparation Solutions Colorectal Cancer Screening

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: PEG With Water, PEG With Low-dose Electrolyte Beverage, PEG With Medium-dose Electrolyte Beverage.
Who it may be relevant to
Registry conditions: Colonoscopy, Bowel Preparation Solutions, Colorectal Cancer Screening. Basic parameters: 18 years — 75 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Randomized Controlled Trial of Different Ratios of Electrolyte Beverage and Water Combined With Polyethylene Glycol on Bowel Preparation Quality and Ingestion Rhythm Before Colonoscopy

Overview

This randomized controlled trial aims to evaluate the effects of different ratios of electrolyte beverage and water combined with polyethylene glycol (PEG) on bowel preparation quality before colonoscopy. Participants undergoing elective colonoscopy will be randomly assigned to one of three bowel preparation regimens: PEG prepared with water only, PEG prepared with a low ratio of electrolyte beverage and water, or PEG prepared with a medium ratio of electrolyte beverage and water. The primary outcome is adequate bowel preparation assessed by the Boston Bowel Preparation Scale (BBPS). Secondary outcomes include bowel preparation completion rate, tolerability, adverse events, repeat colonoscopy rate, adenoma detection rate, and ingestion rhythm characteristics during bowel preparation. This study also aims to explore whether electrolyte beverage-assisted bowel preparation may improve bowel cleansing quality by influencing participants' ingestion rhythm and adherence during PEG intake.

Interventions

  • Other PEG With Water
    Polyethylene glycol (PEG) prepared with water only for bowel preparation before colonoscopy.
  • Other PEG With Low-dose Electrolyte Beverage
    Polyethylene glycol (PEG) prepared with electrolyte beverage and water at a 1:3 ratio for bowel preparation before colonoscopy.
  • Other PEG With Medium-dose Electrolyte Beverage
    Polyethylene glycol (PEG) prepared with electrolyte beverage and water at a 1:1 ratio for bowel preparation before colonoscopy.

Primary outcome measures

  • Adequate Bowel Preparation Rate [Time frame: At the time of colonoscopy on Day 1]
Secondary outcome measures (3)
  • Total Boston Bowel Preparation Scale Score [Time frame: At the time of colonoscopy on Day 1]
  • Bowel Preparation Completion Rate [Time frame: During bowel preparation within 1 hour before colonoscopy on Day 1]
  • Adverse Event Rate [Time frame: During bowel preparation within 1 hour before colonoscopy on Day 1]

Eligibility criteria

Inclusion criteria

  • Adults aged 18-75 years scheduled to undergo elective colonoscopy
  • Meet the standard clinical indications for colonoscopy;
  • Able to understand and comply with the bowel preparation procedure and complete oral polyethylene glycol (PEG) intake as required;
  • Able to comply with study-related data collection and follow-up;
  • Provide written informed consent voluntarily.

Exclusion criteria

  • Previously diagnosed colorectal cancer, intestinal obstruction, or suspected intestinal obstruction;
  • Active gastrointestinal bleeding or a definite history of gastrointestinal bleeding within the past 4 weeks (including melena, hematochezia, or hematemesis);
  • Severe renal insufficiency, decompensated heart failure, significant electrolyte imbalance, or other conditions unsuitable for PEG bowel preparation;
  • Known allergy to polyethylene glycol or components of the electrolyte beverage used in the study;
  • Pregnant or breastfeeding women;
  • Any other condition considered by the investigators to make the participant unsuitable for the study.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Supportive care

Study locations

China · 1 center
  • Nanfang Hospital, Southern Medical University — Guangzhou

Identifiers

NCT: NCT07608120 · NFEC-2026-307

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗