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Recruiting NCT07606794

Supra-Iliac Anterior Quadratus Lumborum Block and Pericapsular Nerve Group (PENG) Block for Analgesia After Total Hip Arthroplasty

No phase Interventional Supra-Iliac Anterior Quadratus Lumborum Block Pericapsular Nerve Group Block Analgesia Total Hip Arthroplasty

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Supra-iliac anterior quadratus lumborum block, Pericapsular nerve group block.
Who it may be relevant to
Registry conditions: Supra-Iliac Anterior Quadratus Lumborum Block, Pericapsular Nerve Group Block, Analgesia, Total Hip Arthroplasty. Basic parameters: 18 years — 75 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

A Randomized Clinical Non-Inferiority Trial Comparing Supra-Iliac Anterior Quadratus Lumborum Block and Pericapsular Nerve Group (PENG) Block for Analgesia After Total Hip Arthroplasty

Overview

This study aims to compare the analgesic efficacy of supra-iliac anterior quadratus lumborum block (SA-QLB) and pericapsular nerve group (PENG) block in patients undergoing total hip arthroplasty (THA).

Detailed description

Total hip arthroplasty (THA) is one of the most common elective orthopedic procedures, performed to restore mobility, alleviate pain and improve quality of life in patients with degenerative hip joint disease. Its rate is projected to further increase with aging of the population worldwide.

Pericapsular nerve group (PENG) block is a fascial block targets periarticular sensory branches derived from the femoral, obturator and accessory obturator nerves innervating the anterior hip capsule.

The ultrasound-guided quadratus lumborum block (QLB) is a regional anesthetic technique with many described approaches: the lateral QL (QL1) block, the posterior QL (QL2) block, and the anterior QL (transmuscular) block.

Interventions

  • Other Supra-iliac anterior quadratus lumborum block
    Patients will receive a supra-iliac anterior quadratus lumborum block (SA-QLB) using 20mL of bupivacaine 0.25%.
  • Other Pericapsular nerve group block
    Patients will receive an ultrasound-guided pericapsular nerve group (PENG) block using 20mL of bupivacaine 0.25%.

Primary outcome measures

  • Degree of pain [Time frame: 12 hours postoperatively]
Secondary outcome measures (5)
  • Total morphine consumption [Time frame: 48 hours postoperatively]
  • Time to the first rescue analgesia [Time frame: 48 hours postoperatively]
  • Time to ambulation [Time frame: Till the first successful mobilization (Up to 4 hours)]
  • Length of hospital stay [Time frame: Till discharge from the hospital (Up to 2 weeks)]
  • Incidence of adverse events [Time frame: 24 hours postoperatively]

Eligibility criteria

Inclusion criteria

  • Age from 18 to 75 years.
  • Both sexes.
  • American Society of Anesthesiologists (ASA) classification I-III.
  • Scheduled for primary elective unilateral total hip arthroplasty (THA) under spinal anesthesia.

Exclusion criteria

  • Known allergies to the drugs used.
  • Infection at the injection site.
  • Bleeding disorders.
  • Recognized neuromuscular disorders.
  • Opioid addiction or dependence.
  • Contraindications to regional anesthesia or peripheral nerve blockade.
  • Body mass index (BMI) > 40 kg/m².
  • Associated decompensated cardiac, hepatic, respiratory, or renal diseases.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Tanta University — Tanta

Identifiers

NCT: NCT07606794 · 36265PR1/4/26

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗