Combination of Superior Hypogastric Plexus Block and Transversus Abdominis Plane Block in Abdominal Hysterectomies
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Superior hypogastric plexus block + Transverse abdominis plane, Superior hypogastric plexus block.
- Who it may be relevant to
- Registry conditions: Superior Hypogastric Plexus Block, Transversus Abdominis Plane Block, Abdominal Hysterectomies. Basic parameters: from 18 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Analgesic Effect of Combination of Superior Hypogastric Plexus Block and Transversus Abdominis Plane Block in Abdominal Hysterectomies: A Randomized Controlled Trial
Overview
This study aims to evaluate the analgesic effect of superior hypogastric plexus block combined with transversus abdominis plane block in abdominal hysterectomies.
Detailed description
Abdominal hysterectomy is a major surgery that is often associated with pronounced postsurgical pain. Inadequate postoperative analgesia can lead to postoperative complications and can delay functional recovery. Accordingly, a multimodal regimen for postoperative pain management is recommended.
The transverse abdominis plane (TAP) block is a regional block anesthetizing the nerves (T10 to L1) hence covering the lower abdominal wall.
The superior hypogastric plexus (SHP), which lies retroperitoneally in front of the L5 and S1 vertebrae, provides innervation to the pelvic viscera. The blockade of SHP is well-recognized for the management of chronic pelvic pain.
Interventions
- Other Superior hypogastric plexus block + Transverse abdominis plane
Patients will receive superior hypogastric plexus block (SHPB) using 20ml of bupivacaine 0.25%+ transverse abdominis plane (TAP) block using 20ml of bupivacaine 0.25%. - Other Superior hypogastric plexus block
Patients will receive superior hypogastric plexus block (SHPB) using 20ml of saline 0.9% (sham)+ transverse abdominis plane (TAP) block using 20ml of bupivacaine 0.25%.
Primary outcome measures
- Time to the first request for the rescue analgesia [Time frame: 24 hours postoperatively]
Secondary outcome measures (4)
- Total morphine consumption [Time frame: 24 hours postoperatively]
- Degree of pain [Time frame: 24 hours postoperatively]
- Quality of recovery [Time frame: 24 hours postoperatively]
- Incidence of adverse events [Time frame: 24 hours postoperatively]
Eligibility criteria
Inclusion criteria
- Age ≥ 18 years.
- American Society of Anesthesiology (ASA) physical status I-II.
- Undergoing abdominal hysterectomies under general anesthesia (GA).
Exclusion criteria
- History of allergies to local anesthetics.
- Body mass index (BMI) >35 kg/m2.
- Opioid dependency.
- Cognitive impairment.
- Bleeding or coagulation disorders.
- Psychiatric and neurological disorder.
- Local infection at the site of injection.
- Severe heart, lung, liver, and renal dysfunction.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Tanta University — Tanta
Identifiers
NCT: NCT07606781 · 36265PR2/4/26