Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Ischemic Preconditioning, Placebo Ischemic Preconditioning.
- Who it may be relevant to
- Registry conditions: Lower Extremity Explosive Power Deficit, Sports Recovery, Basketball Performance, Muscle Fatigue. Basic parameters: 18 years — 25 years · Male.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period: A Randomized Controlled Trial
Overview
This study aimed to evaluate the effects of ischemic preconditioning on lower limb explosive power and post-exercise recovery in basketball players during a 6-week post-season recovery training period. Thirty-four male collegiate basketball players were randomly assigned to either an IPC group or a placebo control group. Bilateral lower limb IPC intervention (3 cycles, each consisting of 5-minute ischemia at 220 mmHg and 5-minute reperfusion, twice per week for 6 weeks) was administered before routine basketball training sessions. Lower limb explosive power, as well as physiological, biochemical, and morphological indices, were assessed before and after the intervention.
Detailed description
Background: Lower limb explosive power is crucial for basketball performance, and effective recovery strategies are key to maintaining training quality. Ischemic preconditioning (IPC) is a non-invasive, economical, and safe method that triggers endogenous protective mechanisms through brief ischemia-reperfusion cycles, showing potential in enhancing athletic performance and metabolic efficiency. However, the effects of IPC on lower limb explosive power during post-match recovery in basketball players remain understudied. Objective: To investigate the effects of a 6-week repeated remote ischemic preconditioning on lower limb explosive power, phosphagen energy system capacity, and physical recovery in male college basketball players. Design: A randomized, parallel-group, placebo-controlled trial with concealed allocation. Participants were randomly assigned to either the IPC experimental group (n=17) or the placebo control group (n=17). Both groups participated in the same regular basketball sessions. The experimental group received bilateral thigh IPC intervention (3×5 minutes, 220 mmHg) before each training session, while the control group received a placebo intervention (3×5 minutes, 20 mmHg). The intervention was administered twice a week for 6 weeks (30 minutes per session). Secondary endpoints: Urinary creatinine coefficient, 10-second maximal load test (blood lactate increment, peak power, mean power), hematological parameters (red blood cell count, hemoglobin, hematocrit, white blood cell count), serum testosterone, cortisol, testosterone/cortisol ratio, body composition (body weight, body fat percentage, BMI), and training load monitoring (heart rate, RPE, urine protein).
Interventions
- Device Ischemic Preconditioning
Bilateral thigh compression was applied using a Theratools pneumatic cuff (T-bfr-0475). Three cycles, each consisting of 5 minutes of ischemia (pressure 220 mmHg) and 5 minutes of reperfusion (total 30 minutes), were performed before regular basketball training sessions. The intervention was conducted twice per week for 6 weeks. Cuff placement: at the inguinal crease of the thigh. Subject position: supine, alternating between left and right legs. - Device Placebo Ischemic Preconditioning
Identical procedure to IPC group except cuff pressure maintained at 20 mmHg (non-ischemic), applied before regular basketball training. Twice weekly for 6 weeks.
Primary outcome measures
- Squat Jump (SJ) height [Time frame: Baseline (Week 0) and Post-intervention (Week 8)]
- Countermovement Jump (CMJ) height [Time frame: Baseline and Week 8]
- Reactive Strength Index (RSI) [Time frame: Baseline and Week 8]
- Standing Long Jump [Time frame: Baseline and Week 8]
- T-Test (T-run) [Time frame: Baseline and Week 8]
- 3/4 Court Sprint [Time frame: Baseline and Week 8]
Secondary outcome measures (4)
- Blood Lactate Accumulation [Time frame: Baseline and Week 8]
- Peak Power (10s Test) [Time frame: Baseline and Week 8]
- Mean Power (10s Test) [Time frame: Baseline and Week 8]
- Testosterone/Cortisol Ratio [Time frame: Baseline and Week 8]
Eligibility criteria
Inclusion criteria
- Male basketball students at Guangzhou Sport University.
- Regular participants in basketball training/practice.
- Healthy adults without cardiovascular, hepatic, renal, digestive, neurological, or metabolic diseases.
- Blood pressure within normal range.
- No history of lower extremity musculoskeletal injury within the past 6 months.
- Not currently using any performance-enhancing substances or medications affecting hormones/metabolism.
- Voluntary participation with signed informed consent.
Exclusion criteria
- Presence of acute or chronic diseases affecting exercise performance.
- History of deep vein thrombosis or coagulation disorders.
- Presence of skin lesions or infections at the thigh cuff placement site.
- Participation in other concurrent lower extremity strength/power training programs outside the study.
- Use of dietary supplements known to affect muscle metabolism within 4 weeks prior to enrollment.
- Inability to complete the full 6-week intervention and testing protocol.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
China · 1 center
- Guangzhou Sport University — Guangzhou
Publications
- Ou Z, Yang L, Zhu H, Weng X, Xu G. Ischemic preconditioning enhances autonomic nervous system modulation during frequency speed of kick test in taekwondo athletes: a randomized crossover study. BMC Sports Sci Med Rehabil. 2026 Feb 12;18(1):136. doi: 10.1186/s13102-026-01602-2. PMID 41680854
- Jean-St-Michel E, Manlhiot C, Li J, Tropak M, Michelsen MM, Schmidt MR, McCrindle BW, Wells GD, Redington AN. Remote preconditioning improves maximal performance in highly trained athletes. Med Sci Sports Exerc. 2011 Jul;43(7):1280-6. doi: 10.1249/MSS.0b013e318206845d. PMID 21131871
- Cheng CF, Kuo YH, Hsu WC, Chen C, Pan CH. Local and Remote Ischemic Preconditioning Improves Sprint Interval Exercise Performance in Team Sport Athletes. Int J Environ Res Public Health. 2021 Oct 12;18(20):10653. doi: 10.3390/ijerph182010653. PMID 34682399
- Chen Y, Yang J, Muradov O, Li X, Lee JKW, Qiu J. Effect of ischemic preconditioning on maximum accumulated oxygen deficit in 400-meter runners. Eur J Sport Sci. 2023 May;23(5):789-796. doi: 10.1080/17461391.2022.2064769. Epub 2022 Apr 25. PMID 35400298
- Carvalho L, Barroso R. Ischemic Preconditioning Improves Strength Endurance Performance. J Strength Cond Res. 2019 Dec;33(12):3332-3337. doi: 10.1519/JSC.0000000000002846. PMID 30844989
- Caru M, Levesque A, Lalonde F, Curnier D. An overview of ischemic preconditioning in exercise performance: A systematic review. J Sport Health Sci. 2019 Jul;8(4):355-369. doi: 10.1016/j.jshs.2019.01.008. Epub 2019 Jan 23. PMID 31333890
- Bailey TG, Jones H, Gregson W, Atkinson G, Cable NT, Thijssen DH. Effect of ischemic preconditioning on lactate accumulation and running performance. Med Sci Sports Exerc. 2012 Nov;44(11):2084-9. doi: 10.1249/MSS.0b013e318262cb17. PMID 22843115
Identifiers
NCT: NCT07604948 · GZSU-IPC-BB-2024