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Enrolling by invitation NCT07604142

Allogenic Bone Block for Oro-Antral Communication Closure for Subsequent Implant Placement

No phase Interventional Tooth Loss

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Extraction will be performed atraumatically using a piezotome surgical motor with an extraction kit.
Who it may be relevant to
Registry conditions: Tooth Loss. Basic parameters: from 20 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Novel Application of CAD-CAM Designed Allogenic Bone Block in Oro-Antral Communication Closure for Subsequent Implant Placement: Radiographic and Histological Analysis

Overview

13 patients will be included in this study with a badly destructed upper molar indicated for extraction. Cone beam computerized tomography images revealed the presence of a large bone defect associated with oro-antral communication with the maxillary sinus. after extraction, The prefabricated allogenic scaffold will be seated. then 6 months later, implant will be inserted.

Detailed description

13 patients will be included in this study with a badly destructed upper molar indicated for extraction. Cone beam computerized tomography images revealed the presence of a large bone defect associated with oro-antral communication with the maxillary sinus. : Extraction will be performed atraumatically using a piezotome surgical motor with an extraction kit. After removal of tooth, oro-antral communication will be verified .The prefabricated CAD-CAM allogenic bone will be seated and covered with nonporous d-PTFE membrane which was secured with simple interrupted sutures. After 6 months, a new CBCT scan will be performed. A mucoperiosteal flap will be reflected ,and a bone biopsy will be taken using a trephine bur. Under strictly aseptic circumstances, the selected implant will be inserted

Interventions

  • Device Extraction will be performed atraumatically using a piezotome surgical motor with an extraction kit
    Extraction will be performed atraumatically using a piezotome surgical motor with an extraction kit. After removal of tooth, oro-antral communication will be verified .The prefabricated CAD-CAM Allogenic bone will be seated and covered with nonporous d-PTFE membrane

Primary outcome measures

  • the integration of graft [Time frame: 6 months]
  • histological analysis of graft [Time frame: 6 months]

Eligibility criteria

Inclusion criteria

  • ≥ 20 badly destructed upper molar indicated for extraction CBCT revealed the presence of a large bone defect associated with oro-antral communication with the maxillary sinus

Exclusion criteria

  • any systemic disesse affect healing heavy smoker sinus disease

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Faculty of Dentistry — Tanta

Identifiers

NCT: NCT07604142 · 456789

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗