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Not yet recruiting NCT07602985

Evaluation of Different Patterns PHMM Root Tears

— Observational Medial Meniscus Knee Injury

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: MRI.
Who it may be relevant to
Registry conditions: Medial Meniscus Knee Injury. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Evaluation Of Different Patterns Of Posterior Horn Medial Meniscus Root Tears

Overview

1. To evaluate and classify different morphological patterns of posterior horn medial meniscus root tears (PHMMRTs) and assess their correlation with clinical presentation, MRI findings, and arthroscopic features. 2. To determine the association between tear patterns and degree of meniscal extrusion. 3. To evaluate the relationship between tear patterns and articular cartilage degeneration. 4. To identify predictors of specific tear patterns based on clinical and radiological findings

Detailed description

The medial meniscus posterior horn root plays a pivotal role in maintaining normal knee biomechanics by converting axial loads into circumferential hoop stresses. Injury to this structure leads to loss of meniscal function, increased tibiofemoral contact pressure, and accelerated degeneration of articular cartilage, resembling the biomechanical effects of total meniscectomy.

Posterior horn medial meniscus root tears (PHMMRTs) present with various morphological patterns, including radial tears, oblique tears, complex tears, and complete root avulsions. Each tear pattern has distinct clinical, radiological, and arthroscopic characteristics, which may influence management strategies and prognosis. Despite increasing recognition of these injuries, data correlating tear patterns with clinical presentation and imaging findings remain limited.

Despite increasing recognition of PHMMRTs, limited studies have comprehensively correlated different tear patterns with clinical, radiological, and arthroscopic findings in a single prospective cohort. This study aims to fill this gap and provide clinically applicable correlations that may guide decision-making and prognosis assessment

Interventions

  • Radiation MRI
    all population should do MRI

Primary outcome measures

  • different morphological patterns of posterior horn medial meniscus root tears. [Time frame: Baseline]
Secondary outcome measures (1)
  • Correlation between meniscal tear pattern and articular cartilage degeneration [Time frame: Baseline]

Eligibility criteria

Inclusion criteria

  • Patients aged ≥18 years (no upper age limit, as PHMMRTs are prevalent in elderly population)
  • Clinical suspicion of medial meniscal injury
  • MRI-confirmed posterior horn medial meniscus root tear
  • Patients undergoing diagnostic or therapeutic knee arthroscopy

Exclusion criteria

  • Previous surgical intervention to the affected knee
  • Lateral meniscus root tears
  • Advanced knee osteoarthritis (Kellgren-Lawrence grade IV)
  • Inflammatory or rheumatoid arthritis
  • Acute ligamentous injuries requiring immediate surgical intervention

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Center list to be confirmed — check the primary protocol.

Publications

  • Lubowitz JH, Provencher MT, Poehling GG. Arthroscopy Techniques achieves PubMed Central citation, yet knee and shoulder outcome failures represent a challenge, and a presidential address prepares us for adversity. Arthroscopy. 2013 Sep;29(9):1461-2. doi: 10.1016/j.arthro.2013.06.012. No abstract available. PMID 23992981
  • Zhu JW, Zheng HL, Wang TF, Zhou ZY, Lei L, Guo XJ, Chen YX, Duan GQ. Global Research Trends on Medial Meniscus Posterior Root Tear: A 20-Year Bibliometric Analysis. J Multidiscip Healthc. 2025 Oct 9;18:6595-6605. doi: 10.2147/JMDH.S541028. eCollection 2025. PMID 41099059

Identifiers

NCT: NCT07602985 · PHMM Root Tears

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗