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Not yet recruiting NCT07602686

MRI and Local Anesthesia

No phase Interventional Dental Anesthesia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: ddMRI.
Who it may be relevant to
Registry conditions: Dental Anesthesia. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

MRI Evaluation of Local Anesthesia Administration

Overview

The purpose of this research is to investigate the utility of using dental-dedicated MRI as a measurement tool to observe and evaluate the administration of local anesthesia in dental patients.

Interventions

  • Device ddMRI
    Dental MRI imaging

Primary outcome measures

  • Patient reported sensation - 5min [Time frame: 5 minutes after the nerve block]
  • Patient reported sensation - 1 hour [Time frame: within 1 hour of the nerve block]
  • Ability to sense light touch [Time frame: within 1 hour of the nerve block]
  • Ability to sense pressure [Time frame: within 1 hour of the nerve block]
  • Ability to sense direction of touch (only if can sense VonFrey fibers) [Time frame: within 1 hour of the nerve block]
  • Ability to distinguish sharp versus dull (only if can sense VonFrey fibers) [Time frame: within 1 hour of the nerve block]

Eligibility criteria

Inclusion criteria

  • Adult age 18 or older
  • Health status of American Society of Anesthesiologists (ASA) class 1 or 2
  • Able to provide informed consent
  • Able to appear in person at OMRIC on the days indicated for the study

Exclusion criteria

  • ASA class 3 or higher
  • Pregnant patients
  • Taking any medication that would affect pain perception or interact with local anesthetic
  • Allergic/history of adverse reaction to local anesthetic or any component in the local anesthetic
  • Paresthesia in the area of innervation of Cranial Nerve V3
  • Active infection or abscess in the oral and maxillofacial region
  • History of temporomandibular disorder, maximum incisal opening less than 15mm
  • History of recent dental trauma (within the past 6 months)
  • Dental hypersensitivity
  • Claustrophobia and/or conditions of anxiety or motion disorder (for MRI purposes)
  • Metallic, electronic, or magnetic implants or devices classified as MR Unsafe or Conditional by the American College of Radiology
  • Unable to give informed consent

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Supportive care

Study locations

United States · 1 center
  • University of Minnesota — Minneapolis

Identifiers

NCT: NCT07602686 · STUDY00025764

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗