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Not yet recruiting NCT07602465

The Impact of Blood Pressure Variability During the Induction and Surgical Periods on Postoperative Acute Kidney Injury

— Observational Acute Kidney Injury (AKI)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Acute Kidney Injury (AKI). Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

The goal of this multicenter retrospective cohort study aimed to explore the effect of BPV during anesthesia induction and surgery on the occurrence of postoperative AKI in non-cardiac surgery patients.

Primary outcome measures

  • AKI [Time frame: Within 7 days after surgery.]

Eligibility criteria

Inclusion criteria

  • Undergoing non-cardiac surgery；
  • Adult；

Exclusion criteria

  • Undergoing urological surgeries that partially directly affect kidney function (including relief of urinary tract obstruction, nephrectomy, or kidney transplantation);
  • Surgery duration less than 60 minutes;
  • Weight < 30 kg or BMI > 35 kg/m2;
  • Patients who underwent reoperation within 7 days after surgery;
  • Surgeries not performed under general anesthesia;
  • ASA > IV;
  • No serum creatinine measurement available within 6 months before surgery (baseline value) or within 7 days after surgery;
  • Preexisting renal dysfunction or a diagnosis of chronic kidney disease before surgery (creatinine > 443 μmol/L);
  • No invasive blood pressure monitoring during the anesthesia induction period, or missing more than 25% of intraoperative invasive blood pressure data collection.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Cohort

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07602465 · 2025ZDSYLL420

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗