Recruiting NCT07600827
Isokinetic Training With Blood Flow Restriction for Patellofemoral Pain Syndrome
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Isokinetic Training, Isokinetic Training Combined With Blood Flow Restriction, Aerobic Cycling Exercise.
- Who it may be relevant to
- Registry conditions: Patellofemoral Pain Syndrome. Basic parameters: 18 years — 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effects of Isokinetic Training Combined With Blood Flow Restriction in Patellofemoral Pain Syndrome
Overview
This randomized controlled trial aims to investigate the effects of isokinetic training combined with blood flow restriction (BFR) in individuals with patellofemoral pain syndrome (PFPS).
Interventions
- Device Isokinetic Training
Participants in this group will receive supervised isokinetic muscle strength training targeting the knee musculature using an isokinetic dynamometer. Each session will last 30 minutes throughout the intervention period. - Device Isokinetic Training Combined With Blood Flow Restriction
Participants in this group will receive isokinetic muscle strength training combined with blood flow restriction (BFR). BFR will be applied to the proximal thigh using a pneumatic cuff at an individualized pressure based on limb occlusion pressure. Isokinetic training will target the knee musculature using an isokinetic dynamometer under supervised conditions. Each session will last 30 minutes, with training performed multiple times per week throughout the intervention period. - Device Aerobic Cycling Exercise
Participants in this group will receive supervised aerobic cycling exercise using a stationary bicycle. Training will be performed at a moderate intensity for 30 minutes per session throughout the intervention period.
Primary outcome measures
- Anterior Knee Pain Scale (AKPS) [Time frame: From enrollment to the end of treatment at 4 weeks]
Eligibility criteria
Inclusion criteria
- Participants aged 18 to 40 years.
- Clinical diagnosis of patellofemoral pain syndrome (PFPS).
- Presence of anterior or retropatellar knee pain for at least 3 months.
- Pain provoked by at least two activities that increase patellofemoral joint load, including squatting, stair climbing, running, jumping, prolonged sitting, or kneeling.
- Average knee pain intensity of ≥3 on a 10-point visual analog scale (VAS) during aggravating activities.
- Ability to participate in exercise training and attend scheduled intervention sessions.
- Willingness to provide written informed consent.
Exclusion criteria
- History of knee surgery or significant trauma to the lower extremity within the previous 12 months.
- Clinical evidence of other knee disorders, including ligament injury, meniscal injury, patellar instability, osteoarthritis, or tendinopathy.
- Presence of neurological, cardiovascular, or systemic musculoskeletal disorders that may affect lower limb function or exercise participation.
- Current participation in other structured lower extremity rehabilitation or strength training programs.
- Contraindications to blood flow restriction training, including uncontrolled hypertension, vascular disease, thromboembolic disorders, or clotting abnormalities.
- Use of pain-relieving injections or surgical interventions for knee pain within the previous 6 months.
- Pregnancy.
- Inability to complete the assessment or intervention procedures.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
China · 1 center
- Nanjing Mingzhou Rehabilitation Hospital — Nanjing
Identifiers
NCT: NCT07600827 · NJKF202602001