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Recruiting NCT07599254

Effect of Two Different Irrigation Protocols and Activation Techniques on Postoperative Pain in Single-visit Endodontic Retreatment: Prospective Randomized Clinical Trial

Phase IV Interventional Apical Periodontitis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: root canal irrigation.
Who it may be relevant to
Registry conditions: Apical Periodontitis. Basic parameters: 18 years — 60 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The relationship between different root canal irrigation techniques and pain after root canal treatment

Interventions

  • Drug root canal irrigation
    Root canal irrigation and postoperative pain

Primary outcome measures

  • Evaluation of the relationship between different root canal irrigation techniques and post-canal treatment pain using surveys. [Time frame: 3-5 month]

Eligibility criteria

Inclusion criteria

  • o Patients aged 18-60 years who are classified as medically healthy (ASA I or II),
  • Mature, single-rooted and canal teeth that had root canal treatment at least four years ago,
  • Teeth with previous root canal obturation 2-4 mm short of the apex,
  • Teeth that do not need periodontal and prosthetic treatment and whose periapical index score (PAI) is between 2 and 4 ,
  • Teeth with single root and canal diagnosed with asymptomatic apical periodontitis,
  • Teeth suitable for rubber dam isolation.

Exclusion criteria

  • o Patients who had taken analgesics, antibiotics, or corticosteroids within two weeks before root canal retreatment,
  • Teeth exhibiting periodontal attachment loss,
  • Presence of vertical root fractures, external root resorption, or perforations,
  • Teeth with retained broken instruments,
  • Non-restorable teeth,
  • Patients in the pregnancy and breastfeeding period.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Turkey (Türkiye) · 1 center
  • Erciyes University — Kayseri

Identifiers

NCT: NCT07599254 · 2025/2

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗