Essential Oils for Urinary Symptoms in Multiple Sclerosis Patients
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Essential Oil Blend (Lavender, Rosemary), Neutral Carrier Oil (Apricot Kernel Oil).
- Who it may be relevant to
- Registry conditions: Multiple Sclerosis (MS), Neurogenic Bladder Disorder, Urinary Incontinence (UI), Urinary Urgency. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Algeria
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Efficacy and Safety of Essential Oil Aromatherapy on Neurogenic Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis: A Randomized Single-Blind Placebo-Controlled Clinical Trial.
Overview
The goal of this clinical trial is to learn if essential oil aromatherapy works to improve urinary symptoms in adults with multiple sclerosis. It will also learn about the safety of essential oil use in this population. The main questions it aims to answer are: * Does essential oil aromatherapy reduce urinary urgency, frequency, and incontinence episodes in participants with multiple sclerosis? * What medical problems do participants have when using essential oil aromatherapy? Researchers will compare essential oil aromatherapy to a placebo (a look-alike neutral oil with no therapeutic properties) to see if essential oil aromatherapy works to improve urinary symptoms in multiple sclerosis patients. Participants will: * Use essential oil aromatherapy or a placebo oil every day for 6 weeks * Complete a urinary symptom scales to record the frequency, urgency, and any leakage episodes each day * Fill out quality of life questionnaires at the beginning and end of the study
Interventions
- Other Essential Oil Blend (Lavender, Rosemary)
This intervention consists of a standardized topical blend of Lavender (Lavandula angustifolia) at 3% and Rosemary (Rosmarinus officinalis) at 2%, diluted in apricot kernel oil as a carrier. The blend was formulated to target neurogenic lower urinary tract symptoms in patients with multiple sclerosis, based on the antispasmodic properties of Lavender and the neuromodulatory and anti-inflammatory properties of Rosemary. The essential oils used are batch-controlled for chemical purity and concentr - Other Neutral Carrier Oil (Apricot Kernel Oil)
This intervention consists of pure Apricot Kernel oil, used as an inert placebo comparator. The placebo oil contains no active essential oils or therapeutic compounds. It is identical to the experimental intervention in terms of appearance, color, viscosity, volume, packaging, and method of application, ensuring effective masking of participants and outcome assessors. The placebo oil is applied topically via gentle circular massage on the lower abdomen, for a total duration of 6 consecutive week
Primary outcome measures
- Overactive Bladder Symptom Score (OABSS) [Time frame: Baseline, and Week 6]
- Qualiveen questionnaire [Time frame: Baseline and Week 6]
Eligibility criteria
Inclusion criteria
- Confirmed diagnosis of Multiple Sclerosis (any form)
- Documented lower urinary tract symptoms defined by an Overactive Bladder Symptom Score (OABSS) ≥ 3 at screening
- Age between 18 and 65 years
- Willing and able to provide written informed consent
- Capable of performing daily topical self-application of the study oil, or having a caregiver available to assist throughout the study period
Exclusion criteria
- Active urinary tract infection confirmed by urine culture at screening
- Pre-existing urological condition unrelated to Multiple Sclerosis (e.g., bladder cancer, benign prostatic hyperplasia, or interstitial cystitis)
- Known allergy or hypersensitivity to essential oils, apricot kernel oil, lavender, or rosemary
- Active skin lesions, wounds, or dermatological conditions on the lower abdomen at the intended site of application
- Pregnancy, breastfeeding, or planning to become pregnant during the study period
- Significant cognitive impairment preventing understanding of study procedures or completion of questionnaires
- Current use of an indwelling urinary catheter or practice of intermittent self-catheterization
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Supportive care
Study locations
Algeria · 2 centers
- Aboubakr abdelmadjid — Oran
- Zitouni-Nourine Saida Hanane — Oran
Identifiers
NCT: NCT07599189 · UO1-HE-SEP-URO-2025-001