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Not yet recruiting NCT07599020

Measuring the Changes of the Intraocular Pressure After Corneal Cross Linking Using Corvis CT

No phase Interventional Keratoconus Intraocular Pressure

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Corvis Machine.
Who it may be relevant to
Registry conditions: Keratoconus, Intraocular Pressure. Basic parameters: 19 years — 35 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

To evaluate the changes that occur in the intraocular pressure before and after corneal cross linking using Corvis CT.

Detailed description

This study will be prospective study. 50 Patients will be included who will undergo corneal cross linking from the out-patient clinic of Tanta University hospital between December 2025 and December 2026 will be included in the study .

Patient with age 19 till 35 years old will be included

Patient with Corneal scarring, Previous corneal infections, Minimum corneal thickness at the thinnest location less than 400 µm, History of uveitis or ocular allergy and Pre-existing glaucoma will be excluded from the study

All patient will undergo full ophthalmological examination. including best corrected visual acuity, degree of myopia , average kertometry and intraocular pressure will be measured before and after cross linkage with three different techniques including Shiotz tonometry, appalanation tonometry and CORVIS machine

Interventions

  • Device Corvis Machine
    Measuring the intraocular pressure

Primary outcome measures

  • Intraocular pressure will be measured by using Corvis CT before cross linking and one month after cross linking [Time frame: Through the end of the study in approximately one year]

Eligibility criteria

Inclusion criteria

  • Patients who will corneal cross linking for mild degree of keratoconus, age between 19 and 35 years old

Exclusion criteria

  • Corneal scarring.
  • Previous corneal infections.
  • Minimum corneal thickness at the thinnest location less than 400 µm.
  • History of uveitis or ocular allergy.
  • Pre-existing glaucoma.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Diagnostic

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07599020 · 36264PR131099/12/25

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗