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Recruiting NCT07597772

Preliminary Trial of SNA014 for Pancreatic Cancer

Early Phase I Interventional Pancreatic Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: 68Ga-NODAGA-SNA006.
Who it may be relevant to
Registry conditions: Pancreatic Cancer. Basic parameters: 18 years — 75 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

A Clinical Study on the Use of ⁶⁸Ga-labelled Claudin 18.2 as a Contrast Agent in Combination With PET/CT for the Imaging of Pancreatic Cancer

Overview

68Ga labeled Claudin 18.2 contrast agent combined with PET/CT for pancreatic cancer

Interventions

  • Drug 68Ga-NODAGA-SNA006
    Administration

Primary outcome measures

  • The safety and tolerability profile of [68Ga]Ga-NODAGA-SNA014 in patients with CLDN18.2-positive pancreatic cancer. [Time frame: 1 week]
  • CLDN18.2-targeting ability of [68Ga]Ga-NODAGA-SNA014 in patients with CLDN18.2-positive pancreatic cancer. [Time frame: 1 week]
  • CLDN18.2-targeting ability of [68Ga]Ga-NODAGA-SNA014 in patients with CLDN18.2-positive pancreatic cancer. [Time frame: 1 week]
  • CLDN18.2-targeting ability of [68Ga]Ga-NODAGA-SNA014 in patients with CLDN18.2-positive pancreatic cancer. [Time frame: 1 week]

Eligibility criteria

Inclusion criteria

  • Aged between 18 and 75 years (inclusive);
  • Possessing legal capacity, voluntarily participating in this clinical trial, and having signed the informed consent form (ICF);
  • Patients with a confirmed diagnosis of pancreatic cancer whose tumours are suitable for Claudin-18.2 testing;
  • Results of gastroscopy, CT, MRI or PET-CT scans performed within the past month (if available);
  • Pathology test results from within the past year;

Exclusion criteria

  • Patients with other clearly diagnosed malignant tumours;
  • Patients with uncontrolled severe infections, or those with other serious comorbidities;
  • Patients with a life expectancy of ≤3 months;
  • Pregnant or breastfeeding patients, and patients of childbearing potential who refuse to use appropriate contraception during the trial;
  • Patients deemed unsuitable for participation in this study by the investigator.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Diagnostic

Study locations

China · 1 center
  • Tianjin Medical University Cancer Institute and Hospital — Tianjin

Identifiers

NCT: NCT07597772 · SNA014-202501

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗