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Not yet recruiting NCT07592832

EFFECTS OF TWO ANESTHESİA TECHNİQUES ON INFLAMMATORY RESPONSE AND AMİNO ACİD METABOLİSM İN THYROİD SURGERY

No phase Interventional General Anesthesia Cervical Plexus Block Thyroid Surgery

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: General Anesthesia, cervical plexus block.
Who it may be relevant to
Registry conditions: General Anesthesia, Cervical Plexus Block, Thyroid Surgery. Basic parameters: 18 years — 70 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

THE EFFECT OF TWO DİFFERENT ANESTHESİA APPROACHES ON PERİOPERATİVE INFLAMMATORY RESPONSE AND AMİNO ACİD METABOLİSM İN THYROİD SURGERY

Overview

The main aim of this study is to compare the effects of two different anesthesia methods-(1) general anesthesia alone and (2) combination of general anesthesia with cervical plexus block-on postoperative inflammatory process and amino acid metabolism in patients undergoing thyroidectomy.

Interventions

  • Procedure General Anesthesia
    In our study, one patient group will receive only general anesthesia, while the other group will receive general anesthesia in addition to ultrasound-guided cervical plexus block. The inflammatory response is a natural response of the body's immune system to surgical trauma, and it can vary depending on the anesthetic agent used. In regulating this response, molecules such as IL-1β, TNF-α, IL-6, IL-10, and IL-40 are important indicators that determine the severity and duration of inflammation.
  • Procedure cervical plexus block
    In our study, one patient group will receive only general anesthesia, while the other group will receive general anesthesia in addition to ultrasound-guided cervical plexus block.

Primary outcome measures

  • Perioperative Inflammatory Response [Time frame: Before the procedure, and at 2 and 6 hours after the procedure.]
  • Inflammatory Response [Time frame: Before the procedure, and at 2 and 6 hours after the procedure.]

Eligibility criteria

Inclusion criteria

  • This includes patients aged 18-70 years
  • classified as ASA I-III
  • who have undergone elective thyroidectomy.

Exclusion criteria

  • Patients who did not wish to participate in the study voluntarily
  • patients for whom superficial cervical block was contraindicated
  • pregnant and breastfeeding women
  • patients in ASA IV-V groups were excluded from the study.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07592832 · Perioperative Inflammatory Res

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗