AI-GF-GNW on Prolonged Grief Reactions
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: AI-Assisted Grief-Focused Guided Narrative Writing, No-Feedback Guided Narrative Writing, Free Writing.
- Who it may be relevant to
- Registry conditions: Artificial Intelligence (AI), Prolonged Grief Symptoms, Depression - Major Depressive Disorder, Anxiety. Basic parameters: 10 years — 19 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
AI-Assisted Grief-Focused Guided Narrative Writing for Subclinical Prolonged Grief Disorder in Bereaved Chinese Adolescents: A Three-Arm Parallel Randomized Controlled Trial.
Overview
Prolonged Grief Disorder (PGD) is a severe, disabling condition characterized by intense yearning and difficulty accepting the reality of loss, which significantly impairs the academic and psychosocial functioning of bereaved adolescents. While Grief-Focused Cognitive Behavioral Therapy (GF-CBT) is effective, its high cost and resource-intensive nature limit its accessibility for adolescents in mainland China. Grief-Focused Guided Narrative Writing (GF-GNW) offers a scalable, low-cost alternative that facilitates memory integration. Furthermore, integrating Artificial Intelligence (AI) to provide personalized, structured feedback has the potential to simulate therapist functions and enhance intervention efficacy. However, the specific efficacy of AI-assisted feedback in this context remains empirically unvalidated. This parallel randomized controlled trial aims to examine the effectiveness of AI-assisted GF-GNW (AI-GF-GNW) in treating Chinese adolescents (aged 10-19) with subclinical PGD, compared to a no-feedback NF-GF-GNW group and a free writing group. Primary outcomes include PGD symptom severity, while secondary outcomes assess depression, anxiety, and daily functioning. We hypothesize that both active intervention arms will significantly alleviate PGD and related symptoms compared to the free writing group, and that the AI-GF-GNW group will demonstrate a significantly greater reduction in symptoms and functional impairment than the NF-GF-GNW group.
Interventions
- Behavioral AI-Assisted Grief-Focused Guided Narrative Writing
Participants will independently complete the intervention writing tasks via the H5 platform. Participants were required to complete a 6-day, 3-session narrative writing task. Each session requires more than 20 minutes of uninterrupted writing. Session 1 requires describing the specific details and feelings of the bereavement event; Session 2 requires describing the negative impact of the event and one's own negative feelings; Session 3 requires a description of the positive impact of the event a - Behavioral No-Feedback Guided Narrative Writing
All processes are the same as the AI-GF-GNW group, except that when participants complete their writing and submit, the platform will only display a "submission successful" prompt and will not provide any feedback on the writing content. - Behavioral Free Writing
Participants in the FWG will not receive structured guidance, and are only required to write freely about their loss experiences. The writing sessions will follow the same schedule and duration as the other groups.
Primary outcome measures
- Prolonged Grief Disorder-13-Revision (PG-13-R) [Time frame: Baseline (0 Day), post-treatment assessment (5 Day), follow-up assessment (35 Day)]
- Patient Health Questionnaire (PHQ-9) [Time frame: Baseline (0 Day), post-treatment assessment (5 Day), follow-up assessment (35 Day)]
Secondary outcome measures (2)
- Generalized Anxiety Disorder (GAD-7) [Time frame: Baseline (0 Day), post-treatment assessment (5 Day), follow-up assessment (35 Day)]
- WHO Disability Assessment Schedule-short version(WHODAS 2.0) [Time frame: Baseline (0 Day), post-treatment assessment (5 Day), follow-up assessment (35 Day)]
Eligibility criteria
Inclusion criteria
- Junior and senior high school students currently studying in Chinese Mainland, aged 10-19;
- Between 6 and 60 months prior to the experimental period, experienced the death of a significant family member or close friend or close friend;
- The total symptom score of PG-13-R is between 20-29 points;
- Ability to write and understand written guidelines, to use the mobile phone to interact with AI;
- Consent to participate in the study.
Exclusion criteria
- Diagnosed or previously diagnosed with mental illness
- The bereavement time does not meet the time window
- PG-13-R score is not within the range
- At present, there is suicidal ideation or recent severe self harm behavior (Reynolds' Suicidal Ideation Questionnaire, SIQ-JR-4>0), and a crisis intervention hotline is provided when necessary.
- Has received other grief counseling or is currently taking psychiatric medication within the past month
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Treatment
Study locations
China · 1 center
- Peking University — Beijing
Identifiers
NCT: NCT07589088 · AI-assisted Grief-Focused GNW