Superior HypogastrIc plExus bLock During Laparoscopic Colorectal Cancer Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Superior hypogastric plexus block.
- Who it may be relevant to
- Registry conditions: Colorectal Cancer (Diagnosis), Laparoscopic Surgery, Superior Hypogastric Plexus Block. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Superior Hypogastric Plexus Block for Early Recovery After Laparoscopic Colorectal Cancer Surgery: A Randomized Controlled Trial
Overview
This trial seeks to assess the efficacy of a superior hypogastric plexus block for early quality of recovery after laparoscopic colorectal cancer surgery.
Detailed description
This study is a single-center, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy of superior hypogastric plexus block (SHPB) in improving the quality of postoperative recovery in patients undergoing laparoscopic colorectal cancer surgery. A total of 170 eligible patients will be enrolled and randomly assigned in a 1:1 ratio to receive either SHPB or placebo block. The primary outcome is the 15-item Quality of Recovery (QoR-15) score at 24 hours postoperatively. Secondary outcomes include visceral pain numerical rating scale (NRS) scores at rest and during movement within 48 hours postoperatively, morphine consumption, time to first flatus, incidence of postoperative ileus, length of hospital stay, and inflammatory cytokine levels (such as interleukin-6 and C-reactive protein). This study aims to elucidate the evidence-based medical position of SHP block within the Enhanced Recovery After Surgery (ERAS) strategy for laparoscopic colorectal cancer surgery.
Interventions
- Procedure Superior hypogastric plexus block
After establishing pneumoperitoneum in laparoscopic colorectal cancer surgery, the superior hypogastric plexus block will be performed on all patients. The block will contain 20 mL of 0.75% ropivacaine hydrochloride or 0.9% normal saline. The injection will be performed by tenting the presacral peritoneum, aspirating with a laparoscopic needle-tip syringe to ensure extravascular placement, and injecting the block.
Primary outcome measures
- Quality of recovery [Time frame: Up to postoperative day 2]
Secondary outcome measures (7)
- Postoperative Pain Scores [Time frame: Up to postoperative day 2]
- Postoperative Opioid Use [Time frame: Up to postoperative day 2]
- The Brief Pain Inventory (BPI) [Time frame: Up to postoperative day 90]
- The McGill Pain Questionnaire [Time frame: Up to postoperative day 90]
- Length of stay in post-anesthesia care unit (PACU) area [Time frame: Postoperative day 1]
- Postoperative nausea and vomiting [Time frame: Up to postoperative day 2]
- Length of hospital stay [Time frame: Up to 3 months after surgery]
Eligibility criteria
Inclusion criteria
- Able to provide informed consent.
- Undergoing elective laparoscopic radical resection for colorectal cancer.
- American Society of Anesthesiologists Physical Status (ASA) class I-III.
Exclusion criteria
- Allergy to block medication (s).
- Coagulation dysfunction.
- Local or systemic infection.
- Unable to cooperate with the completion of the study protocol.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Quadruple blind
- Primary purpose
- Prevention
Study locations
China · 1 center
- The Sixth Affiliated Hospital of Sun Yet-set University — Guangzhou
Identifiers
NCT: NCT07579780 · E2025271