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Recruiting NCT07576270

Effect of Resisted Deep Breathing and Myofascial Release in Postmastectomy

No phase Interventional Post Mastectomy Lymphedema

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Resisted Deep Breathing, Myofascial release.
Who it may be relevant to
Registry conditions: Post Mastectomy Lymphedema. Basic parameters: 45 years — 64 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Pakistan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Combined Effect of Resisted Deep Breathing and Myofascial Release on Pain, Respiratory Efficiency, Chest Mobility and Lymph Edema in Postmastectomy

Overview

This study aims to determine the combined effect of resisted deep breathing and Myofascial release on pain, respiratory efficiency, chest mobility and lymph edema in Postmastectomy.

Detailed description

The study will be randomized controlled trial and will conducted in Shokat Khanam hospital and Anmol cancer hospital. Non-probability convenience sampling technique will be used and 48 participants will be recruited in study after randomization. The subjects will be divided into two group. Group A will receive myofascial release. Group B will receive myofascial release with resisted deep breathing. Both Group will receive Baseline treatment which is including transcutaneous electrical nerve stimulation. The total duration of treatment will be 12 weeks and there will be 2 sessions each week. The tools that will be used are Numeric Pain Rating Scale (NPRS) for pain, Circumferential limb measurements for chest mobility or lymph edema and Spirometer for respiratory efficiency. After data collection will be analyzed by using SPSS version 21.

Interventions

  • Other Resisted Deep Breathing
    The total duration of treatment will be 12 weeks and there will be 2 sessions each week
  • Other Myofascial release
    The total duration of treatment will be 12 weeks and there will be 2 sessions each week

Primary outcome measures

  • Spirometer [Time frame: 12th week]
  • Circumferential limb measurements [Time frame: 12th week]
  • Numerical pain rating scale (NPRS) [Time frame: 12th week]
  • Chest Mobility [Time frame: 12th week]

Eligibility criteria

Inclusion criteria

  • Radiation therapy and chemotherapy was finished at least three months
  • 6 months after mastectomy for breast cancer being diagnosed without lymphedema or with stage 1 lymphedema
  • Complete unilateral Mastectomy
  • pain and having one or more of the following symptoms: heaviness, numbness, oppression, stiffness, alterations in the function, or mobility of the limited shoulder range of motion.

Exclusion criteria

  • Presence of shoulder pathologies for which surgical indications exist
  • Musculoskeletal injury in adjacent areas (shoulder or neck etc.)
  • bilateral surgery for the treatment of breast cancer
  • Bilateral lymphadenectomy
  • Open wounds on upper limbs
  • Circulatory disorders
  • History of shoulder surgery for reasons other than breast cancer.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Pakistan · 1 center
  • Riphah medical center — Lahore

Publications

  • Vijayakumar C, Jain A, Kalaranjani M, Kumbhar US, Kumar N, Sreenath GS. Effectiveness of Myofascial Release Compared to Manual Lymphatic Drainage in Reducing Post-Treatment Shoulder Pain and Stiffness Among Patients Who Underwent Breast Cancer Surgery and Adjuvant Radiotherapy: Randomised controlled trial. Sultan Qaboos Univ Med J. 2025 May 2;25(1):328-335. doi: 10.18295/2075-0528.2841. PMID 40641717
  • Sun R, Liao Y. The impact of combined Gua Sha and myofascial release techniques on upper limb dysfunction in patients with breast cancer and axillary web syndrome: a prospective case series study. Support Care Cancer. 2025 Mar 12;33(4):270. doi: 10.1007/s00520-025-09259-2. PMID 40072712
  • Lara-Palomo IC, Castro-Sanchez AM, Cordoba-Pelaez MM, Albornoz-Cabello M, Ortiz-Comino L. Effect of Myofascial Therapy on Pain and Functionality of the Upper Extremities in Breast Cancer Survivors: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2021 Apr 21;18(9):4420. doi: 10.3390/ijerph18094420. PMID 33919315
  • Kim Y, Park EY, Lee H. The effect of myofascial release in patients with breast cancer-related lymphedema: a cross-over randomized controlled trial. Eur J Phys Rehabil Med. 2023 Feb;59(1):85-93. doi: 10.23736/S1973-9087.22.07698-5. Epub 2023 Jan 13. PMID 36637800
  • AMANY RAW, FATMA SA, NANCY HA, ASHRAF EEJTMJoCU. Effect of Resisted Deep Breathing on Post Mastectomy Lymphedema. 2024;91(12):1443-8.

Identifiers

NCT: NCT07576270 · REC/RCR & AHS/25/0507

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗