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Recruiting NCT07574827

Candida Albicans in Syrian Patients With Periodontitis

Observational Periodontal Disease Periodontal Diseases Periodontitis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Periodontal Assessment and Sample Collection from Subgingival Pockets.
Who it may be relevant to
Registry conditions: Periodontal Disease, Periodontal Diseases, Periodontitis. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Syria
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Prevalence and Impact of Candida Albicans in Syrian Patients With Periodontitis: A Cross-Sectional Study

Overview

Periodontitis is a significant oral health issue characterized by inflammation and destruction of the supporting structures of the teeth. Recent research has indicated that Candida albicans, a common fungal pathogen, may play a role in the exacerbation of periodontal diseases. This study aims to investigate the prevalence and impact of Candida albicans in Syrian patients diagnosed with periodontitis, contributing to a better understanding of its role in oral health within this population.

Interventions

  • Diagnostic test Periodontal Assessment and Sample Collection from Subgingival Pockets
    Clinical examination to assess periodontal status. Collection of subgingival plaque samples for microbiological analysis to identify Candida Albicans.

Primary outcome measures

  • Detection of Candida Species in Subgingival Samples [Time frame: At enrollment]
Secondary outcome measures (1)
  • Periodontal Screening and Recording Index [Time frame: At enrollment]

Eligibility criteria

Inclusion criteria

  • Patients aged 18 years and older.
  • Diagnosed with chronic periodontitis based on clinical examination (attachment loss, probing depth).
  • Consent to participate in the study.

Exclusion criteria

  • Patients with systemic diseases affecting oral health (e.g., diabetes, immunosuppressive conditions).
  • Recent antibiotic or antifungal treatment within the last three months.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Case-control

Study locations

Syria · 1 center
  • Al-Hawash Private University, Faculty of Dentistry — Homs

Identifiers

NCT: NCT07574827 · 06-05-2025

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗