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Not yet recruiting NCT07568106

Adductor Canal Block With or Without Biceps Femoris Short Head Block in Total Knee Arthroplasty

No phase Interventional Total Knee Arthroplasty

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Adductor Canal Block, Biceps Femoris Short Head Block, Sham Biceps Femoris Short Head Block.
Who it may be relevant to
Registry conditions: Total Knee Arthroplasty. Basic parameters: 18 years — 80 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Effect of Adding a Biceps Femoris Short Head Block to an Adductor Canal Block on Postoperative Pain and Functional Outcomes After Total Knee Arthroplasty: A Randomized Controlled Trial

Overview

Total knee arthroplasty is associated with moderate to severe postoperative pain, which may delay mobilization and recovery. Multimodal analgesia including regional anesthesia techniques is widely used to improve outcomes. The adductor canal block (ACB) provides anteromedial knee analgesia but may not adequately cover the posterolateral region. The biceps femoris short head (BiFeS) block is a novel motor-sparing regional anesthesia technique targeting the posterolateral capsule of the knee. This randomized controlled trial aims to compare the analgesic efficacy and functional outcomes of ACB combined with BiFeS block versus ACB alone in patients undergoing total knee arthroplasty. The primary outcome is posterior knee pain at postoperative 6 hours. Secondary outcomes include pain scores within 48 hours, opioid consumption, early and late functional recovery, and opioid-related adverse effects.

Interventions

  • Procedure Adductor Canal Block
    Ultrasound-guided adductor canal block performed with injection of local anesthetic into the adductor canal to block the saphenous nerve and provide postoperative analgesia following total knee arthroplasty.
  • Procedure Biceps Femoris Short Head Block
    Ultrasound-guided biceps femoris short head block performed with injection of local anesthetic between the biceps femoris short head and femur to target the posterolateral innervation of the knee for postoperative analgesia.
  • Procedure Sham Biceps Femoris Short Head Block
    Sham ultrasound-guided biceps femoris short head block performed with injection of normal saline at the same anatomical location to maintain blinding without providing active analgesia.

Primary outcome measures

  • Posterior Knee Pain Intensity [Time frame: 6 hours postoperatively]
Secondary outcome measures (7)
  • Postoperative Pain Intensity [Time frame: 30 minutes, 1, 6, 12, 24, and 48 hours postoperatively]
  • Total Opioid Consumption [Time frame: 0-48 hours postoperatively]
  • Rescue Analgesic Use [Time frame: 0-48 hours postoperatively]
  • Functional Recovery [Time frame: 24 hours, 48 hours, and 6 weeks postoperatively]
  • Quadriceps Muscle Strength [Time frame: Preoperatively, 24 hours, 48 hours, and 6 weeks postoperatively]
  • Time to First Ambulation [Time frame: Within 48 hours postoperatively]
  • Patient Satisfaction [Time frame: 48 hours postoperatively]

Eligibility criteria

Inclusion criteria

  • ASA I-III
  • Adult patients undergoing unilateral primary TKA
  • Planned spinal anesthesia
  • Written informed consent

Exclusion criteria

  • Coagulopathy
  • Drug allergy
  • BMI > 35
  • Renal/hepatic failure
  • Chronic pain or opioid use
  • Depression or psychiatric disorder
  • Revision or bilateral TKA
  • Neurological deficits
  • Preoperative ROM < 90°

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Quadruple blind
Primary purpose
Treatment

Study locations

Turkey (Türkiye) · 1 center
  • Cukurova University — Adana

Identifiers

NCT: NCT07568106 · CU-BiFeS-2026

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗