Menu
Not yet recruiting NCT07564063

Enhanced Recovery After Surgery in Hysterectomy Patients

No phase Interventional Enhanced Recovery After Surgery (ERAS) Protocol

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: dextrose (5%), ERAS protocols.
Who it may be relevant to
Registry conditions: Enhanced Recovery After Surgery (ERAS) Protocol. Basic parameters: 18 years — 70 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Effectiveness of Enhanced Recovery After Surgery (ERAS) Protocols in Hysterectomy Patients. A Prospective,Randomized Controlled Clinical Trial.

Overview

This prospective randomized controlled clinical trial aims to evaluate the effectiveness of Enhanced Recovery After Surgery (ERAS) protocols in patients undergoing elective hysterectomy. ERAS is an evidence-based perioperative approach designed to reduce surgical stress, accelerate recovery, and improve clinical outcomes. Participants will be randomized to receive either ERAS-based care or conventional perioperative management. The study will assess whether ERAS implementation reduces hospital stay and improves postoperative recovery without increasing complications.

Detailed description

Enhanced Recovery After Surgery (ERAS) protocols are structured, multidisciplinary perioperative care pathways developed to optimize surgical outcomes by minimizing physiological stress and promoting early recovery. These protocols include preoperative counseling, shortened fasting with carbohydrate loading, opioid-sparing anesthesia, early feeding, and early mobilization.

Hysterectomy remains one of the most common gynecological procedures worldwide and is often associated with prolonged hospital stay and postoperative morbidity, particularly in resource-limited settings. While international evidence supports the benefits of ERAS in improving outcomes such as reduced length of hospital stay, improved pain control, and decreased complications, there is a need for locally generated data to validate its effectiveness in Egyptian tertiary healthcare settings.

This study will be conducted at Kasr Al-Ainy Hospital, Cairo University, and will include women undergoing elective hysterectomy for benign or early-stage malignant gynecological conditions. Participants will be randomly assigned to either the ERAS group or the conventional care group. Outcomes will be assessed during hospitalization and up to 30 days postoperatively.

Interventions

  • Drug dextrose (5%)
    IV dextrose infusion (5%) 500 ml once ,2-3 hours before anesthesia
  • Procedure ERAS protocols
    Reduced fasting Early oral feeding Early mobilization

Primary outcome measures

  • length of hospital stay (LOS) [Time frame: From day of surgery up to 7 postoperative days]
Secondary outcome measures (2)
  • postoperative pain score [Time frame: At 12 and 24 hours postoperatively]
  • time to first bowel movement [Time frame: Up to 5 postoperative days]

Eligibility criteria

Inclusion criteria

  • Women aged 18-70 years.
  • Undergoing elective total hysterectomy for benign or early stage malignant gynacological conditions .
  • ASA ( American Society of Anesthesiologists ) physical status I-II.
  • Able to provide informed consent.

Exclusion criteria

  • Emergency hysterectomy
  • Advanced malignant requiring extensive debulking
  • Known bowel disease or previous bowel surgery ( crohn's disease , bowel obstruction )
  • Significant cognitive impairment or psychiatric illness
  • Inability to follow ERAS protocol (e.g., cognitive impairment)
  • Refusal to participate

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Supportive care

Study locations

Egypt · 1 center
  • faculty of medicine-Cairo university — Cairo

Identifiers

NCT: NCT07564063 · MS-729-2025

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗