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Recruiting NCT07557199

Promoting Interventions for Climate Change to Upscale Resilience in District Astore

No phase Interventional Climate Change Health Behavior / Well-Being Disaster Planning

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Community Interventions, Primary Healthcare Intervention.
Who it may be relevant to
Registry conditions: Climate Change, Health Behavior / Well-Being, Disaster Planning. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Pakistan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Promoting Interventions for Climate Change to Upscale Resilience (PICCTURE) Trial in District Astore

Overview

The PICCTURE trial is a cluster randomized controlled study that will be conducted in District Astore, Pakistan, to evaluate the effectiveness of community-based interventions in improving resilience to climate-related hazards. The study compares community-led adaptation and resilience strategies and community interventions integrated with primary healthcare engagement against a control group. The objective is to determine whether these approaches improve household-level resilience, adaptive capacity, and health-related outcomes in a mountainous, climate-vulnerable population.

Detailed description

District Astore, located in the mountainous region of Gilgit-Baltistan, is highly vulnerable to climate-related risks, including glacial lake outburst floods (GLOFs), landslides, extreme weather events, and rising temperatures. Its rugged terrain, geographic isolation, dependence on climate-sensitive livelihoods, and limited infrastructure exacerbate the impact of environmental shocks on health and socioeconomic conditions. These vulnerabilities make Astore an appropriate setting to evaluate scalable interventions aimed at strengthening community resilience.

This study is a three-arm cluster randomized controlled trial conducted, where cluster is a village or group of villages. From total available clusters, 30 clusters will be randomly selected and allocated equally across three study arms. Within each cluster, households will be selected through simple random sampling following a complete household listing.

Two intervention arms and one control arm are included. The first intervention arm delivers structured, community-led adaptation and resilience activities through Village Management Committees (VMCs), formed with representation from local stakeholders including elders, teachers, and vulnerable households. The second intervention arm builds upon this approach by incorporating formal engagement of Lady Health Workers and primary healthcare providers to strengthen health-related components, improve service linkage, and enhance outreach to high-risk populations. The control arm does not receive additional inputs.

Intervention components, informed by prior vulnerability assessments, include training and capacity-building on disaster preparedness and response, livelihood diversification, financial literacy, and health awareness. These are delivered through participatory group sessions, simulation exercises, and community mobilization activities over a one-year period. Training sessions are conducted monthly during the initial six months and bi-monthly thereafter, using standardized curricula adapted to the local context.

Primary outcomes are changes in the Disaster Resilience Index (DRI) and Multidimensional Livelihood Vulnerability Index (MLVI), assessed at baseline and endline. Secondary outcomes include health care-seeking, morbidity and mortality, nutrition, environmental resilience, and mental health. Process indicators evaluate intervention delivery, participation, and preparedness mechanisms such as emergency planning, financial coping strategies, and household disaster preparedness. A rapid assessment will be conducted if a major climate-related hazard occurs during the study period to estimate real-world impact under disaster conditions.

Analysis follows an intention-to-treat approach, applying mixed-effects regression models to account for clustering at the community level. Difference-in-differences (DID) estimation will be used to assess intervention effects over time while adjusting for relevant covariates.

This trial will generate context-specific evidence on the effectiveness of integrated community and health system approaches in enhancing resilience in coastal, climate-affected populations, with potential implications for scale-up in similar settings.

Interventions

  • Other Community Interventions
    A structured package of community-led activities delivered through Village Management Committees, including participatory training on disaster risk reduction, livelihood diversification, financial literacy, and health awareness to strengthen household and community resilience.
  • Other Primary Healthcare Intervention
    Lady Health Workers and primary healthcare providers to reinforce interventions delivered through VMCs and strengthen linkages between communities and health services.

Primary outcome measures

  • Household disaster resilience (DRI) [Time frame: At baseline and endline (12 month)]
  • Household vulnerability [Time frame: At baseline and endline (12 month)]
Secondary outcome measures (3)
  • Food security [Time frame: At baseline and endline (12 month)]
  • Mental Health [Time frame: At baseline and endline (12 month)]
  • Household dietary diversity [Time frame: At baseline and endline (12 month)]

Eligibility criteria

Inclusion criteria

  • Permanent residents of the selected study area
  • Aged 18 years and above
  • Willing to provide informed consent

Exclusion criteria

1- Temporary residents or non-residents of the study are

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Prevention

Study locations

Pakistan · 1 center
  • Aga Khan University — Karachi

Identifiers

NCT: NCT07557199 · 6200101665/ R19954/53732

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗