Correlation Between Capillary Refill Time and Perfusion Index in Critically Ill Patients
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Microcirculation monitoring, Microcirculation monitoring.
- Who it may be relevant to
- Registry conditions: Shock State, Hemodynamics Instability, Microcirculation, Monitoring. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Correlation Between Capillary Refilling tIme and Perfusion Index in Critically Ill Patients
Overview
Assessment of capillary refill time (CRT) is a cornerstone of tissue perfusion monitoring in critically ill patients. CRT measurement is performed by applying brief and gentle pressure (for a few seconds) to a small area of skin until blanching occurs. CRT is defined as the time, in seconds, required for the skin surface to return to its initial color after release of pressure. Although CRT is a monitoring tool used on a daily basis in emergency departments and critical care units, its practical measurement modalities remain poorly standardized and time-consuming. Consequently, there is no consensus regarding the most reproducible bedside method for CRT assessment. Moreover, repeated CRT measurements during patient management are resource-intensive in terms of medical time and may raise issues related to healthcare staff availability. The perfusion index (PI) is a marker of tissue perfusion derived from a pulse oximetry sensor. This monitoring device is routinely used in all critically ill patients. It is placed on the finger and worn continuously, including during patient transport. Because PI measurement is automatic and continuous, establishing its correlation with CRT could allow for more precise tissue perfusion monitoring while reducing the time burden associated with bedside assessments in critically ill patients.
Interventions
- Other Microcirculation monitoring
Microcirculation monitoring by Capillary Refill Time (CRT) measurements - Other Microcirculation monitoring
Microcirculation monitoring by Perfusion Index (PI) measurements
Primary outcome measures
- Perfusion index (PI) threshold associated with abnormal capillary refill time (CRT) [Time frame: At the inclusion]
Eligibility criteria
Inclusion criteria
- Adult patient.
- Admission within the previous 24 hours, or within 24 hours of the onset of a hemodynamic instability criterion (requirement for vasopressors or fluid resuscitation).
- Absence of patient objection.
Exclusion criteria
- Legal guardianship, curatorship, or judicial protection.
- No social security coverage.
- Morphological abnormalities preventing CRT and IP measurements.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
France · 2 centers
- Service de Réanimation cardio-vasculaire et thoracique, Hôpital Cardiologique louis Pradel — Bron
- Service de Médecine Intensive-Réanimation, Hôpital Édouard Herriot, Hospices Civils de Lyo — Lyon
Identifiers
NCT: NCT07555041 · 69HCL26_0232