Evaluating the Clinical Impact of the Prehabilitation and Recovery for Enabling Potential (PREP) Clinical Care Pathway
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Osteo Arthritis of the Knee. Basic parameters: 18 years — 100 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United Kingdom
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The Evaluating PREP Study aims to determine in whether the PREP Programme has an impact on clinical outcomes for Veterans undergoing TKR. Specifically, we are exploring whether prehabilitation and a week long intense individualised rehabilitation period after TKR surgery has a positive impact on functional and mental outcomes, and whether these are sustained for up to 12 months post-surgery.
Detailed description
There is compelling clinical, methodological, and service-level rationale to implement and evaluate a veteran-specific prehabilitation and rehabilitation pathway. This proposed service, The Prehabilitation and Recovery for Enabling Potential (PREP) Programme, incorporates standardized outcome measures aligned with core domains for Total Knee Replacement (TKR), and addresses the biopsychosocial complexity unique to veteran populations. The PREP Programme aims not only to improve patient-level outcomes but also to contribute meaningful data to an underrepresented area of Orthopaedic rehabilitation research.
The Evaluating PREP Research Study aims to determine in real-time whether the PREP Programme has an impact on clinical outcomes for Veterans undergoing TKR, and whether these are sustained for up to 12 months post-surgery.
The research study plans to collect data from people undergoing the PREP Programme by extracting clinical data as they move through the clinical prehabilitation and rehabilitation programme. The study will also collect data from an additional questionnaire.
Understanding whether individualised prehabilitation prior to TKR and intensive rehabilitation following surgery influences both physical and mental outcomes for Veteran patients could help improve surgical management in the future, leading to better outcomes for this patient population.
Primary outcome measures
- Clinical impact using the Oxford Knee Score [Time frame: From time of total knee replacement, up to 12 months following surgery]
Secondary outcome measures (4)
- Correlation of Baseline PANAS score and primary outcome - the Oxford Knee Score [Time frame: From baseline, up to 12 months post-surgery]
- Correlation of Baseline PANAS score and the PROM - The Western Ontario and McMaster Universities Arthritis Index (WOMAC) Osteoarthritis Index [Time frame: From baseline to 12 months post surgery]
- Incidences of manipulations under anaesthetic [Time frame: From surgery, up to and 12 months following TKR surgery.]
- Practicality of delivering individualised prehabilitation and/or intensive post-operative rehabilitation [Time frame: From baseline, up to 12 months post-surgery]
Eligibility criteria
Inclusion criteria
- Age ≥ 18 years
- Must be a Veteran under the clinical care of an RJAH Veterans Orthopaedic Consultant and participating in the PREP Programme.
- Able to read and speak English.
- Able to demonstrate capacity to provide informed consent.
Exclusion criteria
- Subject is under 18 years of age.
- Subject is not a Veteran, not under the care of an RJAH Veteran's Orthopaedic Consultant, or is not participating in the PREP Programme.
- Unable to read and speak English.
- Unable to demonstrate capacity to provide informed consent.
- Unable, or unwilling to complete questionnaires throughout the duration of the study.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United Kingdom · 1 center
- The Robert Jones and Agnes Hunt Orthopaedic Hospital — Oswestry
Identifiers
NCT: NCT07553806 · RL1 934