Effect of Intraoperative Dexamethasone on Early Postoperative Sleep Quality in Patients Undergoing Nasal Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Dexamethasone, Normal Saline.
- Who it may be relevant to
- Registry conditions: Sleep Disturbance. Basic parameters: from 19 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effect of Intraoperative Dexamethasone on Early Postoperative Sleep Quality in Patients Undergoing Nasal Surgery: A Randomized Controlled Trial
Overview
This study aims to evaluate the effect of intraoperative dexamethasone on early postoperative sleep quality in adult patients undergoing nasal surgery under general anesthesia.
Interventions
- Drug Dexamethasone
Dexamethasone 10 mg will be administered intravenously during induction of general anesthesia. This single-dose corticosteroid is used for its anti-inflammatory and antiemetic effects. All other perioperative management will be conducted according to standard institutional protocols and will be identical to the control group - Drug Normal Saline
normal saline 2cc will be administered intravenously during induction of general anesthesia.
Primary outcome measures
- Richards-Campbell Sleep Questionnaire (RCSQ) score [Time frame: on postoperative day 1]
Secondary outcome measures (3)
- Quality of Recovery-15 (QoR-15) score [Time frame: Postoperative day 1]
- sleep efficiency [Time frame: Postoperative night (day of surgery)]
- Incidence of postoperative nausea and vomiting [Time frame: From end of surgery to postoperative day 1]
Eligibility criteria
Inclusion criteria
- Adults aged 19 years or older undergoing nasal surgery.
Exclusion criteria
- Patients who do not provide informed consent
- Patients with neurological disease or cognitive impairment that may interfere with questionnaire completion
- Patients with pre-existing sleep disorders or those taking sleep medications
- Patients receiving chronic corticosteroid therapy
- Known hypersensitivity to dexamethasone
- Patients with glaucoma
- Patients with poorly controlled diabetes mellitus (HbA1c > 8.0%)
- Patients with peptic ulcer disease
- Pregnant or breastfeeding women
- Patients deemed unsuitable for the study by the investigator (e.g., those requiring postoperative steroid administration for clinical reasons)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Prevention
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07550803 · 2601-116-1712