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Not yet recruiting NCT07549815

Measuring the Changes of the Intraocular Pressure After Corneal Laser Refractive Surgery Using Different Techniques

No phase Interventional Intraocular Pressure Refractive Surgery

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Corvis machine.
Who it may be relevant to
Registry conditions: Intraocular Pressure, Refractive Surgery. Basic parameters: 19 years — 35 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

To evaluate the changes that occur in the intraocular pressure after corneal refractive surgery either PRK , LASIK and femtosecond laser by using Corvis CT results and applanation tonometer

Detailed description

This study will be prospective study. 50 Patients who will undergo refractive surgery referred from the out-patient clinic of Tanta University hospital between December 2025 and December 2026 will be included in the study . The patient will be randomly selected to do either LASIK, PRK or femtosecond laser LASIK

Patients who will undergo refractive surgery either PRK, LASIK or femtosecond laser with age between 19 and 35 years old , Myopia range from (-2.00 to -6.00 Diopter) and to maintain stability of the data we will use only the right eye of each patient will be included on the study

Kertoconus, Corneal scarring, Previous corneal infections, Minimum corneal thickness at the thinnest location less than 400 µm, History of uveitis or ocular allergy and Pre-existing glaucoma will be excluded from the study.

Age, sex, uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest and cycloplegic refraction, Slit lamp biomicroscopy, fundus examination , Central corneal thickness (CCT) and average Keratometer (K) data will be collected

Intraocular pressure will be measured by by two methods : Corvis CT and applanation tonometer for each patient and will be recorded, all the data will be collected before the refractive surgery and one month after refractive surgery

Interventions

  • Other Corvis machine
    Measuring intraocular pressure by different methods and compare the results

Primary outcome measures

  • Measuring intraocular pressure [Time frame: -The data collected will be before that laser surgery and one month after surgery]

Eligibility criteria

Inclusion criteria

  • Age between 19 and 35 years old
  • Myopia range from (-2.00 to -6.00 Diopter) .

Exclusion criteria

  • Kertoconus.
  • Corneal scarring.
  • Previous corneal infections.
  • Minimum corneal thickness at the thinnest location less than 400 µm.
  • History of uveitis or ocular allergy.
  • Pre-existing glaucoma.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Diagnostic

Study locations

Egypt · 1 center
  • Tanta Univeristy Hospital — Tanta

Publications

  • 1. Bailey MD, Zadnik K (2007) Outcomes of LASIK for myopia with FDA-approved lasers. Cornea 26(3):246-254 2. Sridhar MS, Rao SK, Vajpayee RB, Aasuri MK, Hannush S, Sinha R (2002) Complications of laser-in situ-ker- atomileusis. Indian J Ophthalmol 50(4):265-282 3. Mohammadi SF, Nabovati P, Mirzajani A, Ashrafi E, Vakilian B (2015) Risk factors of regression and under- correction in photorefractive

Identifiers

NCT: NCT07549815 · 36264PR1310100/12/25

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗