IVC Collapsibility Index in Lumbar Stabilization Surgery
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In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Lumbar Spine Surgery, Hemodynamic Changes, Intravascular Volume Status. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Hemodynamic Assessment Using the Inferior Vena Cava Collapsibility Index in Patients Undergoing Lumbar Stabilization Surgery
Overview
This study aims to evaluate perioperative hemodynamic changes using the inferior vena cava (IVC) collapsibility index in patients undergoing lumbar stabilization surgery under general anesthesia. The IVC diameter and collapsibility index will be measured using ultrasonography at predefined perioperative time points. Hemodynamic parameters such as blood pressure and heart rate will also be recorded. The study seeks to determine whether the IVC collapsibility index can be used as a non-invasive indicator of intravascular volume status and hemodynamic changes during lumbar spine surgery.
Detailed description
his prospective study aims to evaluate perioperative hemodynamic changes using the inferior vena cava (IVC) collapsibility index in patients undergoing lumbar stabilization surgery under general anesthesia in the prone position. The inferior vena cava diameter will be measured using ultrasonography at different perioperative time points, including the preoperative period, after induction of anesthesia, and before extubation.
The IVC diameter and collapsibility index will be recorded and analyzed to assess changes in intravascular volume status during the perioperative period. In addition to ultrasonographic measurements, hemodynamic parameters such as blood pressure and heart rate will be monitored and recorded.
The study aims to investigate whether the IVC collapsibility index can be used as a non-invasive indicator of intravascular volume status and perioperative hemodynamic changes in patients undergoing lumbar spine surgery.
Primary outcome measures
- Inferior Vena Cava Collapsibility Index [Time frame: Perioperative period (preoperative assessment, after anesthesia induction, and before extubation)]
Secondary outcome measures (1)
- Intraoperative Hypotension Incidence [Time frame: During the intraoperative period]
Eligibility criteria
Inclusion criteria
- Age ≥ 18 years
- Patients classified as ASA physical status I-II-III
- Patients scheduled for elective lumbar spine stabilization surgery under general anesthesia
- Ability to obtain adequate inferior vena cava (IVC) ultrasonographic imaging
- Provision of written informed consent
Exclusion criteria
- Age younger than 18 years
- Emergency surgery
- American Society of Anesthesiologists (ASA) physical status IV
- Patients undergoing revision lumbar stabilization surgery
- Baseline systolic blood pressure >180 mmHg or <90 mmHg
- Heart failure with ejection fraction (EF) <40%
- Pulmonary artery pressure (PAP) >40 mmHg
- Presence of intra-abdominal mass, ascites, or increased intra-abdominal pressure
- Body mass index (BMI) >30 kg/m²
- Pregnancy
- Patients with neurological or psychiatric disorders
- Inability to obtain adequate inferior vena cava (IVC) ultrasonographic imaging
- Refusal to provide written informed consent
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Turkey (Türkiye) · 2 centers
- Trabzon University Faculty of Medicine Kanunı Training and Research Hospital ,Trabzon — Trabzon
- Trabzon University Faculty of Medicine, Kanuni Training and Research Hospital — Trabzon
Publications
- Yoon HK, Lee HC, Chung J, Park HP. Predictive Factors for Hypotension Associated With Supine-to-Prone Positional Change in Patients Undergoing Spine Surgery. J Neurosurg Anesthesiol. 2020 Apr;32(2):140-146. doi: 10.1097/ANA.0000000000000565. PMID 30475290
- Lee S, Kim DY, Han J, Kim K, You AH, Kang HY, Park SW, Kim MK, Kim JE, Choi JH. Hemodynamic changes in the prone position according to fluid loading after anaesthesia induction in patients undergoing lumbar spine surgery: a randomized, assessor-blind, prospective study. Ann Med. 2024 Dec;56(1):2356645. doi: 10.1080/07853890.2024.2356645. Epub 2024 May 24. PMID 38794845
Identifiers
NCT: NCT07549165 · 10496660-2026/25031