Postoperative Analgesia and Recovery Quality in Total Thyroidectomy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Cervical Plexus Block.
- Who it may be relevant to
- Registry conditions: Postoperative Pain. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Association Between Postoperative Analgesic Approaches and Quality of Recovery and Swallowing Pain in Patients Undergoing Elective Total Thyroidectomy: A Prospective Observational Study
Overview
This prospective observational study evaluates the association between postoperative analgesic approaches and recovery outcomes in patients undergoing elective total thyroidectomy. Patients will be followed under routine clinical care without intervention or randomization. The primary outcome is the Quality of Recovery-15 (QoR-15) score at 24 hours. Secondary outcomes include swallowing pain, resting pain, opioid consumption, postoperative nausea and vomiting, and additional analgesic requirement.
Interventions
- Other Cervical Plexus Block
Bilateral intermediate cervical plexus block may be performed as part of routine clinical practice based on the attending anesthesiologist's decision. The study is observational, and no intervention, assignment, or protocol-driven procedure is applied. Patients are managed according to standard perioperative care.
Primary outcome measures
- Quality of Recovery-15 (QoR-15) Total Score [Time frame: 24 hours postoperatively]
Eligibility criteria
Inclusion criteria
- Patients aged 18-75 years
- ASA physical status classification I-III
- Patients scheduled for elective bilateral total thyroidectomy
- Patients undergoing surgery under general anesthesia
- Individuals able to read and understand Turkish and cognitively capable of completing the QoR-15 questionnaire
- Patients providing written informed consent to participate in the study
Exclusion criteria
- Chronic opioid use (≥3 months of regular opioid use)
- Presence of chronic pain syndrome
- Psychiatric illness or cognitive impairment
- History of neurological disease (stroke, dementia, Parkinson's disease, etc.)
- Known allergy to local anesthetic agents
- Previous surgical interventions in the cervical region (including revision thyroid surgery)
- Planned extended surgery with concomitant neck dissection
- Substernal/retrosternal goiter cases (with potential need for sternotomy or additional procedures)
- Emergency surgical procedures
- Patients with ASA physical status IV or higher
- Pregnancy
- Patients expected to require postoperative intensive care
- Patients experiencing intraoperative complications that deviate from the standard monitoring protocol
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-control
Study locations
Turkey (Türkiye) · 1 center
- Istinye Üniversity — Istanbul
Publications
- Wilson L, Malhotra R, Mayhew D, Banerjee A. The analgesic effects of bilateral superficial cervical plexus block in thyroid surgery: A systematic review and meta-analysis. Indian J Anaesth. 2023 Jul;67(7):579-589. doi: 10.4103/ija.ija_806_22. Epub 2023 Jul 14. PMID 37601928
- Mostafa MM, Gamal RM, Ahmed Baiomy AM, Hassan ME, Kamal JM, Ts T, Kotb TA, Elrawas MM. Efficacy of adding dexmedetomidine as adjuvant with bupivacaine in ultrasound-guided intermediate cervical plexus block for thyroidectomy surgery: randomized controlled study. BMC Anesthesiol. 2025 Mar 25;25(1):139. doi: 10.1186/s12871-025-02990-7. PMID 40133795
Identifiers
NCT: NCT07547124 · Serpil Tiroid