A Multiphase Operational and Environmental Assessment of Lunar Surface Habitation, Lunar Gateway Transit Systems, and Acceleration Pathways for Sustained Human Habitation of the Martian Surface
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Habitat Systems Evaluation, Water-Ice Resource Utilization Assessment, EVA and Mobility Operations.
- Who it may be relevant to
- Registry conditions: Extraterrestrial Habitation Systems, Lunar Surface Habitation, Lunar Water-Ice Resource Assessment, In-Situ Resource Utilization (ISRU). Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This study evaluates the operational, environmental, and habitation-system requirements for sustained human presence on the lunar surface, the performance of the Lunar Gateway as a transit and staging architecture, and the pathways required to accelerate readiness for Martian surface habitation. The protocol examines habitat resilience, radiation exposure modeling, life-support continuity, EVA logistics, behavioral health in isolated environments, and systems-engineering workflows across lunar, transit, and Mars-analog environments. Special emphasis is placed on the identification, extraction, processing, and utilization of lunar water-ice deposits as a critical resource for life-support, radiation shielding, and in-situ propellant production. Findings will inform future mission design, habitation module development, and interplanetary operational frameworks.
Detailed description
This multiphase observational and operational protocol investigates the habitation lifecycle across three mission environments: (1) lunar surface habitation systems, (2) Lunar Gateway transit architecture, and (3) Martian surface analog habitats. The study integrates engineering, environmental, behavioral, and operational assessments to characterize requirements for long-duration human habitation beyond Earth orbit, with a specific focus on the role of water-ice resources in sustaining habitation and enabling interplanetary logistics.
The lunar surface phase evaluates habitat stability, environmental control and life-support system (ECLSS) resilience, radiation shielding performance, EVA logistics, mobility constraints, and dust mitigation strategies. A central component of this phase is the assessment of lunar water-ice availability, extraction feasibility, thermal stability, and processing pathways. Water-ice is evaluated as a source for potable water, oxygen generation, hydrogen production, and in-situ propellant manufacturing. Operational workflows, redundancy models, and failure-mode responses are analyzed to determine the feasibility of sustained lunar habitation supported by local resource utilization.
The Lunar Gateway phase examines transit-architecture performance, including docking operations, crew systems behavior, resource transfer workflows, and the continuity of life-support and environmental systems during transit. The study evaluates how water-ice-derived consumables from the lunar surface could be staged, processed, or transferred through the Gateway to support outbound missions. Behavioral health observations and operational stressors are assessed to understand crew performance in confined transit environments.
The Martian surface analog phase focuses on long-duration isolation, dust intrusion mitigation, power redundancy, habitat resilience, and environmental stability under Mars-analog conditions. This phase evaluates the translational pathways required to accelerate readiness for Martian habitation, including the potential use of Martian subsurface ice deposits for life-support, radiation shielding, and fuel production. Comparisons between lunar and Martian ice-resource utilization inform cross-environment operational strategies.
Across all phases, the protocol collects operational, environmental, and systems-engineering data to inform future mission architectures, habitation module design, and interplanetary habitation strategies. The study does not involve FDA-regulated products, biomedical interventions, or human subjects research as defined by federal regulations. All activities occur within controlled operational and engineering environments.
Interventions
- Other Habitat Systems Evaluation
Operational assessment of habitat modules, environmental stability, ECLSS resilience, redundancy models, and failure-mode responses across lunar, transit, and Mars-analog environments. - Other Water-Ice Resource Utilization Assessment
Evaluation of water-ice identification, extraction, thermal stability, processing, and conversion into potable water, oxygen, hydrogen, and in-situ propellant. - Other EVA and Mobility Operations
Testing of EVA logistics, mobility constraints, dust mitigation strategies, and operational workflows in lunar and Mars-analog environments.
Primary outcome measures
- Habitat System Resilience Index (HSRI) [Time frame: 36 months]
- Water-Ice Utilization Efficiency Ratio [Time frame: 36 months]
- Radiation Modeling Accuracy Score [Time frame: 36 months]
Secondary outcome measures (12)
- EVA Task Completion Time [Time frame: 36 months]
- EVA Mobility Constraint Score [Time frame: 36 months]
- Dust Intrusion Index [Time frame: 36 months]
- Life-Support Continuity Score (LSCS) [Time frame: 36 months]
- Behavioral Health Stability Index (BHSI) [Time frame: 36 months]
- Power System Uptime Percentage [Time frame: 36 months]
- Redundancy Activation Success Rate [Time frame: 36 months]
- Power Recovery Time [Time frame: 36 months]
- Particulate Intrusion Reduction Score [Time frame: 36 months]
- Abrasion Resistance Index [Time frame: 36 months]
- Operational Degradation Rate [Time frame: 36 months]
- Transit-to-Surface Operational Continuity Score (TSOCS) [Time frame: 36 months]
Eligibility criteria
Inclusion criteria
- Adults aged 18-65
- Able to participate in isolated, confined, or controlled operational environments
- Prior experience in engineering, environmental systems, analog missions, or mission operations
- Ability to perform EVA-analog tasks and operational workflows
- Willingness to participate in multi-phase lunar, transit, and Mars-analog simulations
Exclusion criteria
- Medical or physical limitations that prevent participation in isolated or operational environments
- Conditions that limit safe participation in EVA-analog tasks
- Inability to comply with operational protocols or safety requirements
- Participation in conflicting operational studies
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- Truway Health, Inc. New York Headquarters — New York
Publications
- Mkaouer B, Jemni M, Amara S, Chaabene H, Tabka Z. Kinematic and kinetic analysis of two gymnastics acrobatic series to performing the backward stretched somersault. J Hum Kinet. 2013 Jul 5;37:17-26. doi: 10.2478/hukin-2013-0021. eCollection 2013. PMID 24146701
Identifiers
NCT: NCT07546461 · THI-LUNAR-GATEWAY-MARS-HAB-001