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Not yet recruiting NCT07545824

Rectus Abdominis Muscle Parameters and Postoperative Opioid Consumption in Geriatric Patients

— Observational Postoperative Pain

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Ultrasound-Guided Rectus Sheath Block.
Who it may be relevant to
Registry conditions: Postoperative Pain. Basic parameters: from 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Association Between Ultrasound-Derived Rectus Abdominis Muscle Thickness and Thickening Fraction and Postoperative Opioid Consumption in Geriatric Patients Undergoing Abdominal Surgery: A Prospective Observational Study

Overview

This prospective observational study aims to evaluate the relationship between ultrasound-derived rectus abdominis muscle thickness and thickening fraction and postoperative opioid consumption in geriatric patients undergoing abdominal surgery. Preoperative ultrasonographic measurements will be performed during routine clinical care, and postoperative pain scores and analgesic requirements will be recorded within the first 24 hours. The findings may help improve individualized analgesic strategies by identifying patient-specific predictors of postoperative opioid needs.

Interventions

  • Other Ultrasound-Guided Rectus Sheath Block
    Ultrasound-guided rectus sheath block will be performed as part of routine clinical practice in geriatric patients undergoing abdominal surgery. No additional intervention will be introduced for study purposes. Ultrasound-derived rectus abdominis muscle thickness and thickening fraction will be measured preoperatively, and postoperative opioid consumption and pain scores will be recorded within the first 24 hours.

Primary outcome measures

  • Postoperative Total Opioid Consumption [Time frame: First 24 hours postoperatively]

Eligibility criteria

Inclusion criteria

  • Age ≥65 years
  • Scheduled for elective midline abdominal surgery
  • ASA physical status I-III
  • Planned to receive bilateral ultrasound-guided rectus sheath block as part of routine clinical practice
  • Provided written informed consent

Exclusion criteria

  • Known allergy or hypersensitivity to local anesthetics
  • Infection or skin lesion at the injection site
  • Systemic infection or sepsis
  • Coagulopathy (INR >1.5 or platelet count <100,000/mm³)
  • Use of therapeutic anticoagulation not safely managed perioperatively
  • History of previous midline laparotomy
  • History of abdominal mesh implantation or abdominal wall reconstruction
  • Significant abdominal wall pathology (e.g., large hernia) affecting anatomy
  • Neuromuscular disease (e.g., myasthenia gravis, ALS, muscular dystrophy)
  • Inability to perform required maneuver for dynamic ultrasound measurement
  • Moderate to severe cognitive impairment or poor cooperation
  • Body mass index (BMI) >40 kg/m²
  • Cachexia or severe malnutrition
  • Chronic opioid use (≥3 months)
  • Chronic pain syndromes requiring regular analgesic use
  • Alcohol or substance abuse
  • Emergency surgery
  • Use of additional regional anesthesia techniques (e.g., epidural, TAP block)
  • Inadequate ultrasound visualization of the target anatomical plane

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Turkey (Türkiye) · 1 center
  • Istinye Üniversity — Istanbul

Publications

  • Jeffries SD, Harutyunyan R, Morse J, Hemmerling TM. Investigation into the clinical performance of rectus sheath block in reducing postoperative pain following surgical intervention: A systematic review and meta-analysis of randomised controlled trials. Indian J Anaesth. 2024 Feb;68(2):142-152. doi: 10.4103/ija.ija_1099_23. Epub 2024 Jan 29. PMID 38435659
  • Choi ES, Cho SH, Kim JH. Relationship between rectus abdominis muscle thickness and metabolic syndrome in middle-aged men. PLoS One. 2017 Sep 15;12(9):e0185040. doi: 10.1371/journal.pone.0185040. eCollection 2017. PMID 28915276

Identifiers

NCT: NCT07545824 · rektus kas kalınlığı

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗